Degradable polymers for tissue engineering

Riemke van Dijkhuizen-Radersma; Lorenzo Moroni; Aart A. van Apeldoorn; Zheng Zhang; Dirk W. Grijpma

doi:10.1016/B978-0-12-370869-4.00007-0

Degradable polymers for tissue engineering

Riemke van Dijkhuizen-Radersma, Lorenzo Moroni, Aart A. van Apeldoorn, Zheng Zhang, Dirk W. Grijpma

Research output: Chapter in Book/Report/Conference proceeding › Chapter › Academic

18 Citations (Scopus)

Abstract

This chapter elaborates the degradable polymers for tissue engineering and their required scaffold material in tissue engineering. It recognizes the examples of degradable polymers broadly used in tissue engineering. Tissue engineering is the persuasion of the body to heal itself through the delivery to appropriate sites of molecular signals, cells, and supporting structures. The technology of tissue engineering is being applied to (re)generate many human tissues and organs. The chapter focuses on basic aspects of polymers used in the preparation of polymeric scaffolds and matrices. An important requirement for a tissue engineering scaffold is that it degrades and resorbs at a rate that matches the formation of new tissue. Degradable polymers are suitable as scaffold material for tissue engineering as interference with the development and growth of new tissue and unwanted long-term reactions are prevented.

Original language	English
Title of host publication	Tissue Engineering
Editors	Clemens A. van Blitterswijk
Place of Publication	Amsterdam
Publisher	Academic Press
Pages	193–221
ISBN (Print)	978-0-032-370869-4
DOIs	https://doi.org/10.1016/B978-0-12-370869-4.00007-0
Publication status	Published - 2008

Keywords

METIS-254019

Access to Document

10.1016/B978-0-12-370869-4.00007-0

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AU - van Apeldoorn, Aart A.

AU - Zhang, Zheng

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PY - 2008

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AB - This chapter elaborates the degradable polymers for tissue engineering and their required scaffold material in tissue engineering. It recognizes the examples of degradable polymers broadly used in tissue engineering. Tissue engineering is the persuasion of the body to heal itself through the delivery to appropriate sites of molecular signals, cells, and supporting structures. The technology of tissue engineering is being applied to (re)generate many human tissues and organs. The chapter focuses on basic aspects of polymers used in the preparation of polymeric scaffolds and matrices. An important requirement for a tissue engineering scaffold is that it degrades and resorbs at a rate that matches the formation of new tissue. Degradable polymers are suitable as scaffold material for tissue engineering as interference with the development and growth of new tissue and unwanted long-term reactions are prevented.

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