Design and properties of a flow-injection analysis cell using potassium-selective ionsensitive field-effect transistors as detection elements

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    Abstract

    The combination of flow-injection analysis (FIA) and chemically modified ion-sensitive field-effect transistors (CHEMFETs) is described. In a wall-jet cell, two identical potassium-selective CHEMFETs were used for a differential measurement using a platinum (pseudo-)reference electrode. Silicone-rubber membrane materials, chemically bound to the SiO2 gate oxide, were used with valinomycin as the ionophore. The optimized FIA system showed a linear response of 56 mV per decade for potassium concentrations above 5 × 10−5 M. Preliminary results of potassium determinations in human serum and urine samples are presented.
    Original languageEnglish
    Pages (from-to)159-166
    Number of pages8
    JournalAnalytica chimica acta
    Volume245
    DOIs
    Publication statusPublished - 1991

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