Design of a hybrid advective-diffusive microfluidic system with ellipsometric detection for studying adsorption

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Abstract

Establishing and maintaining concentration gradients that are stable in space and time is critical for applications that require screening the adsorption behavior of organic or inorganic species onto solid surfaces for wide ranges of fluid compositions. In this work, we present a design of a simple and compact microfluidic device based on steady-state diffusion of the analyte, between two control channels where liquid is pumped through. The device generates a near-linear distribution of concentrations. We demonstrate this via experiments with dye solutions and comparison to finite-element numerical simulations. In a subsequent step, the device is combined with total internal reflection ellipsometry to study the adsorption of (cat)ions on silica surfaces from CsCl solutions at variable pH. Such a combined setup permits a fast determination of an adsorption isotherm. The measured optical thickness is compared to calculations from a triple layer model for the ion distribution, where surface complexation reactions of the silica are taken into account. Our results show a clear enhancement of the ion adsorption with increasing pH, which can be well described with reasonable values for the equilibrium constants of the surface reactions.
Original languageEnglish
Article number034113
Pages (from-to)-
JournalBiomicrofluidics
Volume10
Issue number3
DOIs
Publication statusPublished - 2016

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Microfluidics
Ions
Adsorption
Silicon Dioxide
adsorption
Silica
surface reactions
Equilibrium constants
Ellipsometry
Surface reactions
silicon dioxide
Complexation
Adsorption isotherms
Chemical elements
ion distribution
microfluidic devices
cats
Screening
Coloring Agents
Dyes

Keywords

  • METIS-319526
  • IR-102484

Cite this

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title = "Design of a hybrid advective-diffusive microfluidic system with ellipsometric detection for studying adsorption",
abstract = "Establishing and maintaining concentration gradients that are stable in space and time is critical for applications that require screening the adsorption behavior of organic or inorganic species onto solid surfaces for wide ranges of fluid compositions. In this work, we present a design of a simple and compact microfluidic device based on steady-state diffusion of the analyte, between two control channels where liquid is pumped through. The device generates a near-linear distribution of concentrations. We demonstrate this via experiments with dye solutions and comparison to finite-element numerical simulations. In a subsequent step, the device is combined with total internal reflection ellipsometry to study the adsorption of (cat)ions on silica surfaces from CsCl solutions at variable pH. Such a combined setup permits a fast determination of an adsorption isotherm. The measured optical thickness is compared to calculations from a triple layer model for the ion distribution, where surface complexation reactions of the silica are taken into account. Our results show a clear enhancement of the ion adsorption with increasing pH, which can be well described with reasonable values for the equilibrium constants of the surface reactions.",
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Design of a hybrid advective-diffusive microfluidic system with ellipsometric detection for studying adsorption. / Wang, Lei; Zhao, Cunlu; Duits, Michael H.G.; Wijnperle, Daniël; Mugele, Friedrich Gunther.

In: Biomicrofluidics, Vol. 10, No. 3, 034113, 2016, p. -.

Research output: Contribution to journalArticleAcademicpeer-review

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AU - Wang, Lei

AU - Zhao, Cunlu

AU - Duits, Michael H.G.

AU - Wijnperle, Daniël

AU - Mugele, Friedrich Gunther

PY - 2016

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AB - Establishing and maintaining concentration gradients that are stable in space and time is critical for applications that require screening the adsorption behavior of organic or inorganic species onto solid surfaces for wide ranges of fluid compositions. In this work, we present a design of a simple and compact microfluidic device based on steady-state diffusion of the analyte, between two control channels where liquid is pumped through. The device generates a near-linear distribution of concentrations. We demonstrate this via experiments with dye solutions and comparison to finite-element numerical simulations. In a subsequent step, the device is combined with total internal reflection ellipsometry to study the adsorption of (cat)ions on silica surfaces from CsCl solutions at variable pH. Such a combined setup permits a fast determination of an adsorption isotherm. The measured optical thickness is compared to calculations from a triple layer model for the ion distribution, where surface complexation reactions of the silica are taken into account. Our results show a clear enhancement of the ion adsorption with increasing pH, which can be well described with reasonable values for the equilibrium constants of the surface reactions.

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