Design of blood compatible polymers and polymer surfaces

J. Feijen*

*Corresponding author for this work

    Research output: Contribution to journalConference articleAcademicpeer-review

    2 Citations (Scopus)

    Abstract

    Blood compatible polymers and polymer surfaces are gaining attention for application in medical devices and artificial organs. However, when a polymer surface comes in contact with blood several processes that induce thrombus formation become evident. To control, prevent or suppress these processes, several approaches are used. The first approach is concerned about the preparation of polymer surface with a minimal interfacial free energy with blood. On one hand, the second approach aims to attach aliphatic chains to the surface, to establish a preferential adsorption of albumin. With these approaches, it is expected that various heparinization techniques for polymeric surfaces will be developed.

    Original languageEnglish
    Pages (from-to)1153-1160
    Number of pages8
    JournalMacromolecular reports
    Volume31
    Issue numberSuppl 6-7
    Publication statusPublished - 1 Dec 1994
    Event3rd Euro-American Conference on Functional Polymers and Biopolymers, Macromolecules '92 - Canterbury, United Kingdom
    Duration: 7 Sep 199211 Sep 1992
    Conference number: 3

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