Detection of inhibitory compounds of acetylcholine esterase with a novel ion responding impedance sensor (IRIS)

R.B.M. Schasfoort; T. Niedziela

doi:10.1016/0925-4005(94)87079-9

Detection of inhibitory compounds of acetylcholine esterase with a novel ion responding impedance sensor (IRIS)

R.B.M. Schasfoort^*
, T. Niedziela

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

7 Citations (Scopus)

49 Downloads (Pure)

Abstract

This paper describes the detection of an inhibitor of acetylcholine esterase with a new device. Detection of conductivity changes in a microcavity by the action of the enzyme was measured with the ion responding impedance sensor (IRIS). A model pesticide, paraoxone, was studied with the IRIS. The detection limit for paraoxone with the device was 10^-8 M (3 ppb).

Original language	English
Pages (from-to)	175-177
Number of pages	3
Journal	Sensors and Actuators B: Chemical
Volume	18
Issue number	1-3
DOIs	https://doi.org/10.1016/0925-4005(94)87079-9
Publication status	Published - 1 Jan 1994
Externally published	Yes

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title = "Detection of inhibitory compounds of acetylcholine esterase with a novel ion responding impedance sensor (IRIS)",

abstract = "This paper describes the detection of an inhibitor of acetylcholine esterase with a new device. Detection of conductivity changes in a microcavity by the action of the enzyme was measured with the ion responding impedance sensor (IRIS). A model pesticide, paraoxone, was studied with the IRIS. The detection limit for paraoxone with the device was 10-8 M (3 ppb).",

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AB - This paper describes the detection of an inhibitor of acetylcholine esterase with a new device. Detection of conductivity changes in a microcavity by the action of the enzyme was measured with the ion responding impedance sensor (IRIS). A model pesticide, paraoxone, was studied with the IRIS. The detection limit for paraoxone with the device was 10-8 M (3 ppb).

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DO - 10.1016/0925-4005(94)87079-9

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Detection of inhibitory compounds of acetylcholine esterase with a novel ion responding impedance sensor (IRIS)

Abstract

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