Determinants of compliance withe medication in patients with rheumatoid arthritis: the importance of self-efficacy expectations.

Herman Brus, H.L.M. Brus, Mart A F J van de Laar, Erik Taal, Johannes J. Rasker, O. Wiegman

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In this study we examine which factors are related to compliance with medication in patients suffering from rheumatoid arthritis (RA). Patients: persons suffering recently developed, active RA, who cooperated in a randomized study on the effect of patient education. We analyzed the relation between adherence to Sulphasalazine therapy and personal factors, environmental influences, demographic factors, disease-related factors, and barriers to compliance. Moreover, a logistical regression analysis was performed on these factors, considering 80% a high compliance, both with compliance as dependent factor. Only self-efficacy correlated with compliance (r=0.58; P<0.001). The logistical regression analysis identified self-efficacy as the only factor determining 80% adherence (P=0.01). Self-efficacy regarding the use of prescribed medication is related to compliance with this treatment. Further study is needed to determine the test characteristics of self-efficacy as a predictor for compliance with medication.
Original languageUndefined
Pages (from-to)57-64
Number of pages7
JournalPatient education and counseling
Issue number1
Publication statusPublished - 1999


  • Compliance
  • Rheumatoid Arthritis
  • METIS-148737
  • Patient education
  • IR-73036
  • Self-efficacy

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