Development and validation of a new method for real-time measurement of fluid dynamics during simulated multi-infusion setups

A. M.D. Timmerman, B. Riphagen, J. H.G.M. Klaessens, R. M. Verdaasdonk

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

1 Citation (Scopus)

Abstract

Multi-infusion setups for medication administration in e.g. Intensive Care Units seem uncontrolled due to flow and pressure differences between syringe pumps. To investigate the dynamics and interaction of multi-infusion, a dedicated set-up was developed to measure the concentrations of fluids dynamically in multiple lines using absorption spectral photometry. For feasibility testing and calibration, various dyes and concentrations were investigated to find the optimal settings. The developed method was validated and showed satisfactory results for determining mixtures of up to three different dyes in different ratios. The method was applied in initial simulation experiments for measuring effects of manipulations in a multi-infusion set-up simulating a clinical situation. Results showed evidence for mutual influencing of separate infusion lines. The method developed for measuring the fluid dynamics of multi-infusion will contribute to a better insight and controlled administration of medications.

Original languageEnglish
Title of host publicationWorld Congress on Medical Physics and Biomedical Engineering
Subtitle of host publicationDiagnostic and Therapeutic Instrumentation, Clinical Engineering
Pages718-721
Number of pages4
Edition7
DOIs
Publication statusPublished - 1 Dec 2009
Externally publishedYes
EventWorld Congress on Medical Physics and Biomedical Engineering 2009 - ICM, Munich, Germany
Duration: 7 Sep 200912 Sep 2009

Publication series

NameIFMBE Proceedings
Number7
Volume25
ISSN (Print)1680-0737

Conference

ConferenceWorld Congress on Medical Physics and Biomedical Engineering 2009
CountryGermany
CityMunich
Period7/09/0912/09/09

Keywords

  • Fluid dynamics
  • Multi-infusion system
  • Quality
  • Safety
  • Simultaneous analysis
  • Spectrophotometry

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