Development of a precision system for image-guided needle placement: from scratch to clinic

Maarten Menno Arnolli

    Research output: ThesisPhD Thesis - Research UT, graduation UT

    1358 Downloads (Pure)


    Advances in medical technology enable an ongoing transition from invasive, open surgery to minimally invasive diagnostics and intervention. In the field of oncology, percutaneous techniques have emerged in which biopsy and ablation of tumours are performed via a needle through the skin using image-guidance. The objective of this research is the development of a precision system for image-guided percutaneous needle placement in the thorax and abdomen to improve upon the convenstional freehand method. It covers the entire strategic, architectural and detail design and realization of a complete system from first idea to prototype, its technical verification, its integration in the intervention suite and its pre-clinical validation, up to its first deployment in clinical practice.
    Original languageEnglish
    QualificationDoctor of Philosophy
    Awarding Institution
    • University of Twente
    • Broeders, Ivo Adriaan Maria Johannes, Supervisor
    • Brouwer, Dannis Michel, Supervisor
    • Franken, M.C.J., Co-Supervisor
    Award date24 May 2017
    Place of PublicationEnschede
    Print ISBNs978-90-365-4332-3
    Publication statusPublished - 24 May 2017


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