Development of an item bank to measure factual disease and treatment related knowledge of rheumatoid arthritis patients in the treat to target era

Marieke J. de Jonge (Corresponding Author), Martijn A.H. Oude Voshaar, Anita M.P. Huis, Mart A.F.J. van de Laar, Marlies E.J.L. Hulscher, Piet L.C.M. van Riel

Research output: Contribution to journalArticleAcademicpeer-review

3 Citations (Scopus)


Objective: To develop a Disease and treatment associated Knowledge in RA item bank (DataK-RA) based on item response theory. Methods: Initial items were developed from a systematic review. Rheumatology professionals identified relevant content trough a RAND modified Delphi scoring procedure and consensus meeting. RA patients provided additional content trough a focus group. Patients and professionals rated readability, feasibility and comprehensiveness of resulting items. Cross-sectional data were collected to evaluate psychometric properties of the items. Results: Data of 473 patients were used for item reduction and calibration. Twenty items were discarded based on corrected item-total point biserial correlation <0.30. Confirmatory factor analysis with weighted least squares estimation on the polychoric correlation matrix suggested good fit for a unidimensional model for the remaining 42 items (CFI 0.97 TLI = 0.97, RMSEA = 0.02, WRMR = 0.97), supporting the proposed scoring procedure. Scores were highly reliable and normally distributed with minimal ceiling (1.8%) and no floor effects. 75% of tested hypotheses about the association of DataK-RA scores with related constructs were supported, indicating good construct validity. Conclusion: DataK-RA is a psychometrically sound item bank. Practice implications: DataK-RA provides health professionals and researchers with a tool to identify and target patients’ information needs or to assess effects of educational efforts.
Original languageEnglish
Pages (from-to)67-73
Number of pages7
JournalPatient education and counseling
Issue number1
Early online date21 Jul 2017
Publication statusPublished - 1 Jan 2018


  • Item response theory
  • Item bank
  • Measurement instrument
  • (Patient) education
  • (Patient) knowledge
  • Personalized healthcare
  • Quality indicator
  • Rheumatoid arthritis

Cite this