Dexamethasone nanomedicines for COVID-19

Twan Lammers*, Alexandros Marios Sofias, Roy van der Meel, Raymond Schiffelers, Gert Storm, Frank Tacke, Steffen Koschmieder, Tim H. Brümmendorf, Fabian Kiessling, Josbert M. Metselaar

*Corresponding author for this work

Research output: Contribution to journalComment/Letter to the editorAcademicpeer-review

60 Citations (Scopus)

Abstract

Nano-formulating dexamethasone, and administering it via intravenous injection or inhalation, may help to improve anti-COVID-19 treatment efficacy by targeting the potent corticosteroid drug to hyper-activated immune cells, by potentiating its anti-oedema activity and by exploiting its anti-fibrotic effects.
Original languageEnglish
Pages (from-to)622-624
Number of pages3
JournalNature nanotechnology
Volume15
Issue number8
DOIs
Publication statusPublished - 1 Aug 2020

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