TY - JOUR
T1 - Dexamethasone nanomedicines for COVID-19
AU - Lammers, Twan
AU - Sofias, Alexandros Marios
AU - van der Meel, Roy
AU - Schiffelers, Raymond
AU - Storm, Gert
AU - Tacke, Frank
AU - Koschmieder, Steffen
AU - Brümmendorf, Tim H.
AU - Kiessling, Fabian
AU - Metselaar, Josbert M.
PY - 2020/8/3
Y1 - 2020/8/3
N2 - Nano-formulating dexamethasone, and administering it via intravenous injection or inhalation, may help to improve anti-COVID-19 treatment efficacy by targeting the potent corticosteroid drug to hyper-activated immune cells, by potentiating its anti-oedema activity and by exploiting its anti-fibrotic effects.
AB - Nano-formulating dexamethasone, and administering it via intravenous injection or inhalation, may help to improve anti-COVID-19 treatment efficacy by targeting the potent corticosteroid drug to hyper-activated immune cells, by potentiating its anti-oedema activity and by exploiting its anti-fibrotic effects.
KW - 22/2 OA procedure
UR - http://www.scopus.com/inward/record.url?scp=85088866461&partnerID=8YFLogxK
U2 - 10.1038/s41565-020-0752-z
DO - 10.1038/s41565-020-0752-z
M3 - Comment/Letter to the editor
C2 - 32747742
AN - SCOPUS:85088866461
SN - 1748-3387
VL - 15
SP - 622
EP - 624
JO - Nature nanotechnology
JF - Nature nanotechnology
IS - 8
ER -