TY - JOUR
T1 - Diagnostic Value of Bereitschaftspotential in People With Functional Seizures
AU - Dietze, Christoph S.
AU - van Waart-Houtman, Dieke
AU - Meppelink, Anne Marthe
AU - Bourez-Swart, Mireille
AU - van der Palen, Job
AU - Zijlmans, Maeike
AU - van der Salm, Sandra M.A.
N1 - Publisher Copyright:
Copyright © 2024 by the American Clinical Neurophysiology Society.
PY - 2024/10/3
Y1 - 2024/10/3
N2 - Purpose: Bereitschaftspotential (BP) or readiness potential in people with functional movement disorders can aid diagnostic workup. We evaluated the diagnostic value of BP as an interictal EEG marker in people with functional seizures (FS).Methods: We recorded and analyzed BP interictal before intended movements in 17 adults with FS and 17 controls with alternative diagnoses. We evaluated the signals for the presence of BP, latency, amplitude, and early versus late BP.Results: Bereitschaftspotential was present in all except one person with FS. We found no significant differences in the latency and amplitude of BP between participants with FS and controls. The early BP showed the most significant variance in amplitude, latency, and presence.Conclusions: We found interictal typical BP values in participants with FS and variable semiology, while earlier research found interictal no BP in functional movement disorders. These findings do not support the use of BP as an interictal diagnostic tool for FS. Differences in early BP and focus on FS with pure motor semiology are starting points for further research evaluating potential interictal markers in people with FS.
AB - Purpose: Bereitschaftspotential (BP) or readiness potential in people with functional movement disorders can aid diagnostic workup. We evaluated the diagnostic value of BP as an interictal EEG marker in people with functional seizures (FS).Methods: We recorded and analyzed BP interictal before intended movements in 17 adults with FS and 17 controls with alternative diagnoses. We evaluated the signals for the presence of BP, latency, amplitude, and early versus late BP.Results: Bereitschaftspotential was present in all except one person with FS. We found no significant differences in the latency and amplitude of BP between participants with FS and controls. The early BP showed the most significant variance in amplitude, latency, and presence.Conclusions: We found interictal typical BP values in participants with FS and variable semiology, while earlier research found interictal no BP in functional movement disorders. These findings do not support the use of BP as an interictal diagnostic tool for FS. Differences in early BP and focus on FS with pure motor semiology are starting points for further research evaluating potential interictal markers in people with FS.
KW - n/a OA procedure
KW - Interictal marker
KW - Motor seizures
KW - Pseudoseizures
KW - Psychogenic seizures
KW - Evoked potential
UR - http://www.scopus.com/inward/record.url?scp=85206452577&partnerID=8YFLogxK
U2 - 10.1097/WNP.0000000000001123
DO - 10.1097/WNP.0000000000001123
M3 - Article
C2 - 39358826
AN - SCOPUS:85206452577
SN - 0736-0258
JO - Journal of clinical neurophysiology
JF - Journal of clinical neurophysiology
ER -