Differences in patient characteristics and associations with comorbid load in Dutch and Australian patients

Anke Lenferink, Job van der Palen, Peter Frith, Paul van der Valk, Tanja Effing

Research output: Contribution to journalMeeting AbstractOther research output

Abstract

COPD frequently exists with comorbidities, but inclusion of COPD patients with severe comorbidities in self-management trials is still relatively uncommon.

In a randomised controlled self-management trial COPD patients with ≥ 1 comorbidity were included. We have explored possible differences in patient characteristics between a Dutch and Australian COPD sample, and evaluated associations between comorbid load and patient characteristics using multivariate logistic regression analyses.

In total 201 COPD patients (mean age 68.5 ± 8.9; 64.2% male) were included (Netherlands, n=145, Australia, n=56), and 42.3% had ≥ 2 comorbidities with no differences in comorbid load between both countries (p=0.29), although there were significant baseline differences (p<0.05): Australian patients had worse mMRC dyspnoea, lung function and COPD Assessment Test scores, a higher comorbid depression rate, reported less exercise/week, but had better cognitive function scores and health literacy. In the Dutch patients comorbid load was associated with worse health literacy (OR 2.84, 95% CI 1.37-6.67), less self-reported exercise/week (OR 1.06, 95% CI 1.01-1.12), and stronger fatigue experiences (OR 1.04, 95% CI 1.01-1.06). For the Australian patients it was associated with stronger emotional feelings (OR 2.86, 95% CI 1.43-5.88).

Despite similar inclusion criteria, differences in patient characteristics were observed between Dutch and Australian COPD patients. Comorbid load was associated with different patient characteristics per country. This highlights the need for individual assessments of COPD patients, so that self-management interventions can be tailored to patients' needs and capabilities.

Original languageEnglish
Article numberPA3756
JournalEuropean respiratory journal. Supplement
Volume48
Issue numberSuppl. 60
DOIs
Publication statusPublished - 2016

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Chronic Obstructive Pulmonary Disease
Comorbidity
Self Care
Health Literacy
Exercise
Needs Assessment
Netherlands
Dyspnea
Cognition
Fatigue
Emotions
Logistic Models
Regression Analysis
Depression
Lung

Cite this

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title = "Differences in patient characteristics and associations with comorbid load in Dutch and Australian patients",
abstract = "COPD frequently exists with comorbidities, but inclusion of COPD patients with severe comorbidities in self-management trials is still relatively uncommon.In a randomised controlled self-management trial COPD patients with ≥ 1 comorbidity were included. We have explored possible differences in patient characteristics between a Dutch and Australian COPD sample, and evaluated associations between comorbid load and patient characteristics using multivariate logistic regression analyses.In total 201 COPD patients (mean age 68.5 ± 8.9; 64.2{\%} male) were included (Netherlands, n=145, Australia, n=56), and 42.3{\%} had ≥ 2 comorbidities with no differences in comorbid load between both countries (p=0.29), although there were significant baseline differences (p<0.05): Australian patients had worse mMRC dyspnoea, lung function and COPD Assessment Test scores, a higher comorbid depression rate, reported less exercise/week, but had better cognitive function scores and health literacy. In the Dutch patients comorbid load was associated with worse health literacy (OR 2.84, 95{\%} CI 1.37-6.67), less self-reported exercise/week (OR 1.06, 95{\%} CI 1.01-1.12), and stronger fatigue experiences (OR 1.04, 95{\%} CI 1.01-1.06). For the Australian patients it was associated with stronger emotional feelings (OR 2.86, 95{\%} CI 1.43-5.88).Despite similar inclusion criteria, differences in patient characteristics were observed between Dutch and Australian COPD patients. Comorbid load was associated with different patient characteristics per country. This highlights the need for individual assessments of COPD patients, so that self-management interventions can be tailored to patients' needs and capabilities.",
author = "Anke Lenferink and {van der Palen}, Job and Peter Frith and {van der Valk}, Paul and Tanja Effing",
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language = "English",
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Differences in patient characteristics and associations with comorbid load in Dutch and Australian patients. / Lenferink, Anke ; van der Palen, Job; Frith, Peter; van der Valk, Paul; Effing, Tanja.

In: European respiratory journal. Supplement, Vol. 48, No. Suppl. 60, PA3756, 2016.

Research output: Contribution to journalMeeting AbstractOther research output

TY - JOUR

T1 - Differences in patient characteristics and associations with comorbid load in Dutch and Australian patients

AU - Lenferink, Anke

AU - van der Palen, Job

AU - Frith, Peter

AU - van der Valk, Paul

AU - Effing, Tanja

PY - 2016

Y1 - 2016

N2 - COPD frequently exists with comorbidities, but inclusion of COPD patients with severe comorbidities in self-management trials is still relatively uncommon.In a randomised controlled self-management trial COPD patients with ≥ 1 comorbidity were included. We have explored possible differences in patient characteristics between a Dutch and Australian COPD sample, and evaluated associations between comorbid load and patient characteristics using multivariate logistic regression analyses.In total 201 COPD patients (mean age 68.5 ± 8.9; 64.2% male) were included (Netherlands, n=145, Australia, n=56), and 42.3% had ≥ 2 comorbidities with no differences in comorbid load between both countries (p=0.29), although there were significant baseline differences (p<0.05): Australian patients had worse mMRC dyspnoea, lung function and COPD Assessment Test scores, a higher comorbid depression rate, reported less exercise/week, but had better cognitive function scores and health literacy. In the Dutch patients comorbid load was associated with worse health literacy (OR 2.84, 95% CI 1.37-6.67), less self-reported exercise/week (OR 1.06, 95% CI 1.01-1.12), and stronger fatigue experiences (OR 1.04, 95% CI 1.01-1.06). For the Australian patients it was associated with stronger emotional feelings (OR 2.86, 95% CI 1.43-5.88).Despite similar inclusion criteria, differences in patient characteristics were observed between Dutch and Australian COPD patients. Comorbid load was associated with different patient characteristics per country. This highlights the need for individual assessments of COPD patients, so that self-management interventions can be tailored to patients' needs and capabilities.

AB - COPD frequently exists with comorbidities, but inclusion of COPD patients with severe comorbidities in self-management trials is still relatively uncommon.In a randomised controlled self-management trial COPD patients with ≥ 1 comorbidity were included. We have explored possible differences in patient characteristics between a Dutch and Australian COPD sample, and evaluated associations between comorbid load and patient characteristics using multivariate logistic regression analyses.In total 201 COPD patients (mean age 68.5 ± 8.9; 64.2% male) were included (Netherlands, n=145, Australia, n=56), and 42.3% had ≥ 2 comorbidities with no differences in comorbid load between both countries (p=0.29), although there were significant baseline differences (p<0.05): Australian patients had worse mMRC dyspnoea, lung function and COPD Assessment Test scores, a higher comorbid depression rate, reported less exercise/week, but had better cognitive function scores and health literacy. In the Dutch patients comorbid load was associated with worse health literacy (OR 2.84, 95% CI 1.37-6.67), less self-reported exercise/week (OR 1.06, 95% CI 1.01-1.12), and stronger fatigue experiences (OR 1.04, 95% CI 1.01-1.06). For the Australian patients it was associated with stronger emotional feelings (OR 2.86, 95% CI 1.43-5.88).Despite similar inclusion criteria, differences in patient characteristics were observed between Dutch and Australian COPD patients. Comorbid load was associated with different patient characteristics per country. This highlights the need for individual assessments of COPD patients, so that self-management interventions can be tailored to patients' needs and capabilities.

U2 - 10.1183/13993003.congress-2016.PA3756

DO - 10.1183/13993003.congress-2016.PA3756

M3 - Meeting Abstract

VL - 48

JO - European respiratory journal. Supplement

JF - European respiratory journal. Supplement

SN - 0904-1850

IS - Suppl. 60

M1 - PA3756

ER -