Digital optical phase conjugation of fluorescence in turbid tissue

Ivo Micha Vellekoop, Meng Cui, Changhuei Yang

Research output: Contribution to journalArticleAcademicpeer-review

123 Citations (Scopus)


We demonstrate a method for phase conjugating fluorescence. Our method, called reference free digital optical phase conjugation, can conjugate extremely weak, incoherent optical signals. It was used to phase conjugate fluorescent light originating from a bead covered with 0.5 mm of light-scattering tissue. The phase conjugated beam refocuses onto the bead and causes a local increase of over two orders of magnitude in the light intensity. Potential applications are in imaging, optical trapping, and targeted photochemical activation inside turbid tissue.
Original languageEnglish
Article number081108
Pages (from-to)-
Number of pages4
JournalApplied physics letters
Issue number8
Publication statusPublished - 22 Aug 2012


  • METIS-288644
  • IR-81954


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