Directed Assembly and Development of Material-Free Tissues with Complex Architectures

E Vrij, Jeroen Rouwkema, Vanessa LaPointe, Clemens van Blitterswijk, R.K. Truckenmüller, N.C. Rivron

Research output: Contribution to journalArticleAcademicpeer-review

38 Citations (Scopus)


Material-free tissues are assembled using solely cells. Microstructured hydrogel templates and high content screening allow the formation of centimeter-scale tissues with precise architectures. Similar to developing tissues, these contract autonomously, controllably shift shape, self-scaffold by secreting extracellular matrix, and undergo morphogenesis.
Original languageUndefined
Pages (from-to)4032-4039
Number of pages8
JournalAdvanced materials
Issue number21
Publication statusPublished - 2016


  • IR-100692
  • METIS-316993

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