Directed Assembly and Development of Material-Free Tissues with Complex Architectures

E Vrij, Jeroen Rouwkema, Vanessa LaPointe, Clemens van Blitterswijk, R.K. Truckenmüller, N.C. Rivron

Research output: Contribution to journalArticleAcademicpeer-review

26 Citations (Scopus)

Abstract

Material-free tissues are assembled using solely cells. Microstructured hydrogel templates and high content screening allow the formation of centimeter-scale tissues with precise architectures. Similar to developing tissues, these contract autonomously, controllably shift shape, self-scaffold by secreting extracellular matrix, and undergo morphogenesis.
Original languageUndefined
Pages (from-to)4032-4039
Number of pages8
JournalAdvanced materials
Volume28
Issue number21
DOIs
Publication statusPublished - 2016

Keywords

  • IR-100692
  • METIS-316993

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