Does scaffold architecture influence oxygen gradients in cartilaginous tissue engineered constructs?

J. Malda*, T. Woodfield, F. van der Vloodt, F. Kooy, D.E. Martens, J. Tramper, C.A. van Blitterswijk, J. Riesle

*Corresponding author for this work

    Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

    Abstract

    The oxygen gradients in cartilaginous tissue engineering constructs were evaluated. Spatial distributions of cells within constructs were determined from DAPI stained histological sections using image analysis. The scaffolds were produced using either a compression molding (CM)/salt leaching or 3D fiber deposition (3DF) techniques. The results show that 3DF constructs contain significantly more cartilaginous tissue and cells in the center.

    Original languageEnglish
    Title of host publication7th World Biomaterials Congress 2004
    Subtitle of host publicationMay 17-21, 2004, Sydney, Australia
    Place of PublicationRed Hook, NY
    PublisherCurran Associates Inc.
    Pages747-747
    Number of pages1
    Volume1
    ISBN (Print)978-1-60423-461-9
    Publication statusPublished - 1 Dec 2004
    Event7th World Biomaterials Congress, WBC 2004 - Sydney, Australia
    Duration: 17 May 200421 May 2004
    Conference number: 7

    Conference

    Conference7th World Biomaterials Congress, WBC 2004
    Abbreviated titleWBC
    CountryAustralia
    CitySydney
    Period17/05/0421/05/04

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