Dopamine hydrochloride and carboxymethyl chitosan coatings for multifilament surgical suture and their influence on friction during sliding contact with skin substitute

Gangqiang Zhang*, Ganlin Zheng, Tianhui Ren, Xiangqiong Zeng, Emile van der Heide

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

4 Citations (Scopus)
28 Downloads (Pure)

Abstract

In order to reduce the damage to tissue and fill the interstices between fibers, multifilament sutures are frequently treated with certain coating materials. The objective of this study was to create and characterize dopamine hydrochloride (DA) and carboxymethyl chitosan (CMCS) coatings on surgical sutures and investigate their effects on the frictional performance of the surgical sutures during sliding through a skin substitute. The effects of the treatment on the physical and chemical characteristics of the surgical sutures were evaluated. The friction force of the surgical sutures during sliding through the skin substitute was experimentally determined using a penetration friction apparatus. The coefficient of friction (COF) was calculated using a linear elastic model and was used to estimate the frictional behavior of the surgical suture-skin interactions. The results showed that the DA coating could evenly deposit on the surface of the etched multifilament surgical suture surfaces in a weakly alkaline buffer solution. The CMCS coating material could form a uniform film on the surface of the sutures. Minor changes in the surface roughness of the multifilament surgical sutures with different treatments occurred in this study. The friction force and the COF of the multifilament surgical sutures with DA and CMCS coating showed little change when compared with untreated multifilament surgical sutures.

Original languageEnglish
Pages (from-to)58-69
Number of pages12
JournalFriction
Volume8
Issue number1
Early online date19 Nov 2018
DOIs
Publication statusPublished - 1 Feb 2020

Keywords

  • Biomaterials
  • coating
  • friction
  • skin substitute
  • surgical suture

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