Abstract
We present a droplet-based microfluidic platform for carrying out sequential and multiple reactions. Flexible droplet formation, multiple injections of additional droplets into pregenerated droplets, addressing of droplets into incubation chambers, and dosing of additional droplets to incubated droplets were achieved by the forward/reverse flow direction control and flow path control with pneumatic valves. The droplet incubation chamber array with a great freedom and flexibility in droplet handling makes "Journey of Droplets on a Chip" possible, and also could be applied for performing complex chemical and biological reactions, especially in which incubation and dosing steps are necessary.
| Original language | English |
|---|---|
| Title of host publication | 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013 |
| Publisher | The Chemical and Biological Microsystems Society |
| Pages | 1941-1943 |
| Number of pages | 3 |
| Volume | 3 |
| ISBN (Print) | 9781632666246 |
| Publication status | Published - 2013 |
| Event | 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, μTAS 2013 - Freiburg, Germany Duration: 27 Oct 2013 → 31 Oct 2013 Conference number: 17 |
Conference
| Conference | 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, μTAS 2013 |
|---|---|
| Abbreviated title | MicroTAS |
| Country/Territory | Germany |
| City | Freiburg |
| Period | 27/10/13 → 31/10/13 |
Keywords
- Droplets
- Gradient
- Microfluidics
- Sequential reaction