Droplet microreactor for reaction monitoring at elevated temperatures and pressure

J.C. Vollenbroek; A.E. Nieuwelink; J.G. Bomer; R.M. Tiggelaar; A. van den Berg; B.M. Weckhuysen; M. Odijk

Droplet microreactor for reaction monitoring at elevated temperatures and pressure

J.C. Vollenbroek, A.E. Nieuwelink, J.G. Bomer, R.M. Tiggelaar, A. van den Berg, B.M. Weckhuysen, M. Odijk

Biomedical and Environmental Sensorsystems

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review

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Abstract

Recording reaction kinetics in detail and at various reaction conditions can be a time-consuming process. Microdroplets form ideal reaction chambers, suitable for high-throughput studies [1]. We report the fabrication of a microfluidic droplet-based microreactor operating at elevated temperatures (up to 130 °C) and pressures (up to 0.7 MPa), to rapidly study reaction kinetics. As proof-of-principle, the temperature-dependent fluorescence of Rhodamine B in ethanol is monitored [2]. Time-resolved information is obtained by measuring at multiple spots in the microreactor

Original language	English
Title of host publication	MicroTAS
Subtitle of host publication	22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences November 11-15, 2018, Kaohsiung, Taiwan
Editors	Fan-Gang Tseng, Gwo-Bin Lee
Publisher	The Chemical and Biological Microsystems Society
Pages	2131-2133
Number of pages	3
ISBN (Electronic)	978-1-510-89757-1
ISBN (Print)	978-0-578-40530-8
Publication status	Published - 18 Nov 2018
Event	22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2018 - Kaohsiung Exhibition Center, Kaohsiung, Taiwan Duration: 10 Nov 2018 → 15 Nov 2018 Conference number: 22 https://cbmsociety.org/conferences/microtas2018/

Conference

Conference	22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2018
Abbreviated title	MicroTAS 2018
Country/Territory	Taiwan
City	Kaohsiung
Period	10/11/18 → 15/11/18
Internet address	https://cbmsociety.org/conferences/microtas2018/

Keywords

2019 OA procedure
Droplets
Elevated temperature and pressure
Integrated heaters
Reaction monitoring
Microreactor

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Vollenbroek2018dropletFinal published version, 1.09 MBLicence: Taverne

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Vollenbroek, J. C., Nieuwelink, A. E., Bomer, J. G., Tiggelaar, R. M., van den Berg, A., Weckhuysen, B. M., & Odijk, M. (2018). Droplet microreactor for reaction monitoring at elevated temperatures and pressure. In F.-G. Tseng, & G.-B. Lee (Eds.), MicroTAS : 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences November 11-15, 2018, Kaohsiung, Taiwan (pp. 2131-2133). The Chemical and Biological Microsystems Society.

Vollenbroek, J.C. ; Nieuwelink, A.E. ; Bomer, J.G. et al. / Droplet microreactor for reaction monitoring at elevated temperatures and pressure. MicroTAS : 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences November 11-15, 2018, Kaohsiung, Taiwan. editor / Fan-Gang Tseng ; Gwo-Bin Lee. The Chemical and Biological Microsystems Society, 2018. pp. 2131-2133

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title = "Droplet microreactor for reaction monitoring at elevated temperatures and pressure",

abstract = "Recording reaction kinetics in detail and at various reaction conditions can be a time-consuming process. Microdroplets form ideal reaction chambers, suitable for high-throughput studies [1]. We report the fabrication of a microfluidic droplet-based microreactor operating at elevated temperatures (up to 130 °C) and pressures (up to 0.7 MPa), to rapidly study reaction kinetics. As proof-of-principle, the temperature-dependent fluorescence of Rhodamine B in ethanol is monitored [2]. Time-resolved information is obtained by measuring at multiple spots in the microreactor",

keywords = "2019 OA procedure, Droplets, Elevated temperature and pressure, Integrated heaters, Reaction monitoring, Microreactor",

author = "J.C. Vollenbroek and A.E. Nieuwelink and J.G. Bomer and R.M. Tiggelaar and {van den Berg}, A. and B.M. Weckhuysen and M. Odijk",

year = "2018",

month = nov,

day = "18",

language = "English",

isbn = "978-0-578-40530-8",

pages = "2131--2133",

editor = "Fan-Gang Tseng and Gwo-Bin Lee",

booktitle = "MicroTAS",

publisher = "The Chemical and Biological Microsystems Society",

note = "22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2018, MicroTAS 2018 ; Conference date: 10-11-2018 Through 15-11-2018",

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Vollenbroek, JC, Nieuwelink, AE, Bomer, JG , Tiggelaar, RM , van den Berg, A, Weckhuysen, BM & Odijk, M 2018, Droplet microreactor for reaction monitoring at elevated temperatures and pressure. in F-G Tseng & G-B Lee (eds), MicroTAS : 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences November 11-15, 2018, Kaohsiung, Taiwan. The Chemical and Biological Microsystems Society, pp. 2131-2133, 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2018, Kaohsiung, Taiwan, 10/11/18.

Droplet microreactor for reaction monitoring at elevated temperatures and pressure. / Vollenbroek, J.C.; Nieuwelink, A.E.; Bomer, J.G. et al.
MicroTAS : 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences November 11-15, 2018, Kaohsiung, Taiwan. ed. / Fan-Gang Tseng; Gwo-Bin Lee. The Chemical and Biological Microsystems Society, 2018. p. 2131-2133.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review

TY - GEN

T1 - Droplet microreactor for reaction monitoring at elevated temperatures and pressure

AU - Vollenbroek, J.C.

AU - Nieuwelink, A.E.

AU - Bomer, J.G.

AU - Tiggelaar, R.M.

AU - van den Berg, A.

AU - Weckhuysen, B.M.

AU - Odijk, M.

N1 - Conference code: 22

PY - 2018/11/18

Y1 - 2018/11/18

N2 - Recording reaction kinetics in detail and at various reaction conditions can be a time-consuming process. Microdroplets form ideal reaction chambers, suitable for high-throughput studies [1]. We report the fabrication of a microfluidic droplet-based microreactor operating at elevated temperatures (up to 130 °C) and pressures (up to 0.7 MPa), to rapidly study reaction kinetics. As proof-of-principle, the temperature-dependent fluorescence of Rhodamine B in ethanol is monitored [2]. Time-resolved information is obtained by measuring at multiple spots in the microreactor

AB - Recording reaction kinetics in detail and at various reaction conditions can be a time-consuming process. Microdroplets form ideal reaction chambers, suitable for high-throughput studies [1]. We report the fabrication of a microfluidic droplet-based microreactor operating at elevated temperatures (up to 130 °C) and pressures (up to 0.7 MPa), to rapidly study reaction kinetics. As proof-of-principle, the temperature-dependent fluorescence of Rhodamine B in ethanol is monitored [2]. Time-resolved information is obtained by measuring at multiple spots in the microreactor

KW - 2019 OA procedure

KW - Droplets

KW - Elevated temperature and pressure

KW - Integrated heaters

KW - Reaction monitoring

KW - Microreactor

M3 - Conference contribution

SN - 978-0-578-40530-8

SP - 2131

EP - 2133

BT - MicroTAS

A2 - Tseng, Fan-Gang

A2 - Lee, Gwo-Bin

PB - The Chemical and Biological Microsystems Society

T2 - 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2018

Y2 - 10 November 2018 through 15 November 2018

ER -

Vollenbroek JC, Nieuwelink AE, Bomer JG , Tiggelaar RM , van den Berg A, Weckhuysen BM et al. Droplet microreactor for reaction monitoring at elevated temperatures and pressure. In Tseng FG, Lee GB, editors, MicroTAS : 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences November 11-15, 2018, Kaohsiung, Taiwan. The Chemical and Biological Microsystems Society. 2018. p. 2131-2133

Droplet microreactor for reaction monitoring at elevated temperatures and pressure

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