Dynamic imaging with T2* contrast using U-FLARE

David G. Norris*, Mathias Hoehn-Berlage, Frank Wittlich, Tobias Back, Dieter Leibfritz

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

14 Citations (Scopus)
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Dynamic changes in T2* in the rat brain induced by the injection of Gd-DTPA are monitored using the U-FLARE sequence. Sensitivity to T2* is easily introduced into this sequence and may be freely varied. The images obtained display an adequate spatial resolution and contrast, for a temporal resolution of 1 s. Intensity-time curves and parametric images of regional cerebral blood flow (rCBV) are presented for three different blood pCO2 values. The results presented clearly demonstrate that U-FLARE is a viable method for dynamically measuring changes in T2*, and thus has application in imaging of both perfusion and functional activation.

Original languageEnglish
Pages (from-to)921-924
Number of pages4
JournalMagnetic resonance imaging
Issue number7
Publication statusPublished - 1993
Externally publishedYes


  • Perfusion
  • T contrast


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