Dynamic imaging with T2* contrast using U-FLARE

David G. Norris; Mathias Hoehn-Berlage; Frank Wittlich; Tobias Back; Dieter Leibfritz

doi:10.1016/0730-725X(93)90210-5

Dynamic imaging with T₂^* contrast using U-FLARE

David G. Norris^*, Mathias Hoehn-Berlage, Frank Wittlich, Tobias Back, Dieter Leibfritz

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

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Abstract

Dynamic changes in T₂^* in the rat brain induced by the injection of Gd-DTPA are monitored using the U-FLARE sequence. Sensitivity to T₂^* is easily introduced into this sequence and may be freely varied. The images obtained display an adequate spatial resolution and contrast, for a temporal resolution of 1 s. Intensity-time curves and parametric images of regional cerebral blood flow (rCBV) are presented for three different blood pCO₂ values. The results presented clearly demonstrate that U-FLARE is a viable method for dynamically measuring changes in T₂^*, and thus has application in imaging of both perfusion and functional activation.

Original language	English
Pages (from-to)	921-924
Number of pages	4
Journal	Magnetic resonance imaging
Volume	11
Issue number	7
DOIs	https://doi.org/10.1016/0730-725X(93)90210-5
Publication status	Published - 1993
Externally published	Yes

Keywords

Perfusion
T contrast
U-FLARE

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10.1016/0730-725X(93)90210-5

1-s2.0-0730725X93902105-mainFinal published version, 2.03 MB

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abstract = "Dynamic changes in T2* in the rat brain induced by the injection of Gd-DTPA are monitored using the U-FLARE sequence. Sensitivity to T2* is easily introduced into this sequence and may be freely varied. The images obtained display an adequate spatial resolution and contrast, for a temporal resolution of 1 s. Intensity-time curves and parametric images of regional cerebral blood flow (rCBV) are presented for three different blood pCO2 values. The results presented clearly demonstrate that U-FLARE is a viable method for dynamically measuring changes in T2*, and thus has application in imaging of both perfusion and functional activation.",

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T1 - Dynamic imaging with T2* contrast using U-FLARE

AU - Norris, David G.

AU - Hoehn-Berlage, Mathias

AU - Wittlich, Frank

AU - Back, Tobias

AU - Leibfritz, Dieter

PY - 1993

Y1 - 1993

N2 - Dynamic changes in T2* in the rat brain induced by the injection of Gd-DTPA are monitored using the U-FLARE sequence. Sensitivity to T2* is easily introduced into this sequence and may be freely varied. The images obtained display an adequate spatial resolution and contrast, for a temporal resolution of 1 s. Intensity-time curves and parametric images of regional cerebral blood flow (rCBV) are presented for three different blood pCO2 values. The results presented clearly demonstrate that U-FLARE is a viable method for dynamically measuring changes in T2*, and thus has application in imaging of both perfusion and functional activation.

AB - Dynamic changes in T2* in the rat brain induced by the injection of Gd-DTPA are monitored using the U-FLARE sequence. Sensitivity to T2* is easily introduced into this sequence and may be freely varied. The images obtained display an adequate spatial resolution and contrast, for a temporal resolution of 1 s. Intensity-time curves and parametric images of regional cerebral blood flow (rCBV) are presented for three different blood pCO2 values. The results presented clearly demonstrate that U-FLARE is a viable method for dynamically measuring changes in T2*, and thus has application in imaging of both perfusion and functional activation.

KW - Perfusion

KW - T contrast

KW - U-FLARE

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DO - 10.1016/0730-725X(93)90210-5

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SN - 0730-725X

VL - 11

SP - 921

EP - 924

JO - Magnetic resonance imaging

JF - Magnetic resonance imaging

IS - 7

ER -

Dynamic imaging with T₂^* contrast using U-FLARE

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Keywords

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