EANM practice guideline for quantitative SPECT-CT

John C. Dickson, Ian S. Armstrong, Pablo Minguez Gabiña, Ana M. Denis-Bacelar, Aron K. Krizsan, Jonathan M. Gear, Tim Van den Wyngaert, Lioe Fee de Geus-Oei, Ken Herrmann*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

24 Citations (Scopus)
9 Downloads (Pure)


Purpose: Quantitative SPECT-CT is a modality of growing importance with initial developments in post radionuclide therapy dosimetry, and more recent expansion into bone, cardiac and brain imaging together with the concept of theranostics more generally. The aim of this document is to provide guidelines for nuclear medicine departments setting up and developing their quantitative SPECT-CT service with guidance on protocols, harmonisation and clinical use cases. Methods: These practice guidelines were written by members of the European Association of Nuclear Medicine Physics, Dosimetry, Oncology and Bone committees representing the current major stakeholders in Quantitative SPECT-CT. The guidelines have also been reviewed and approved by all EANM committees and have been endorsed by the European Association of Nuclear Medicine. Conclusion: The present practice guidelines will help practitioners, scientists and researchers perform high-quality quantitative SPECT-CT and will provide a framework for the continuing development of quantitative SPECT-CT as an established modality.

Original languageEnglish
Pages (from-to)980-995
Number of pages16
JournalEuropean journal of nuclear medicine and molecular imaging
Issue number4
Publication statusPublished - Mar 2023


  • Bone
  • Cardiology
  • Dosimetry
  • Neurology
  • Quantification


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