TY - JOUR
T1 - ECG-gated versus nongated three-dimensional intracoronary ultrasound analysis
T2 - Implications for volumetric measurements
AU - Bruining, Nico
AU - von Birgelen, Clemens
AU - de Feyter, Pim J.
AU - Ligthart, Jurgen
AU - Li, Wenguang
AU - Serruys, Patrick W.
AU - Roelandt, Jos R.T.C.
PY - 1998/3/1
Y1 - 1998/3/1
N2 - The quantitative analysis of a three-dimensional (3-D) intracoronary ultrasound (ICUS) image data set permits a more comprehensive assessment of coronary arterial segments. The 3-D image sets are generally acquired during continuous motorized pullbacks. However, the cyclic changes of vascular dimensions and the cyclic spatial displacement of the ICUS transducer relative to the vessel wall can result in characteristic image artifacts, which may limit the applicability of quantitative automated analysis systems. This limitation may be overcome by an ECG-gated image acquisition. In the present study we acquired in vivo (1) nongated and (2) ECG-gated 3-D ICUS image sets of 15 human atherosclerotic coronary arteries and performed a computer-assisted contour detection of the lumen and total vessel boundaries. Total vessel and lumen volumes measured significantly larger in the nongated versus ECG-gated end-diastolic image sets (753 ± 307 mm3 vs. 705 ± 305 mm3 411 ± 154 mm3 vs. 388 ± 165 mm3, both: P < 0.05). Both end-diastolic and systolic measurements were available in nine arteries, showing a larger total vessel and lumen volume at systole (664 ± 221 mm3 vs. 686 ± 227 mm3, P = 0.03; 384 ± 164 mm3 vs. 393 ± 170 mm3, P = 0.08). The differences observed may be of particular interest for volumetric ICUS studies, addressing presumably small differences in vessel or lumen dimensions.
AB - The quantitative analysis of a three-dimensional (3-D) intracoronary ultrasound (ICUS) image data set permits a more comprehensive assessment of coronary arterial segments. The 3-D image sets are generally acquired during continuous motorized pullbacks. However, the cyclic changes of vascular dimensions and the cyclic spatial displacement of the ICUS transducer relative to the vessel wall can result in characteristic image artifacts, which may limit the applicability of quantitative automated analysis systems. This limitation may be overcome by an ECG-gated image acquisition. In the present study we acquired in vivo (1) nongated and (2) ECG-gated 3-D ICUS image sets of 15 human atherosclerotic coronary arteries and performed a computer-assisted contour detection of the lumen and total vessel boundaries. Total vessel and lumen volumes measured significantly larger in the nongated versus ECG-gated end-diastolic image sets (753 ± 307 mm3 vs. 705 ± 305 mm3 411 ± 154 mm3 vs. 388 ± 165 mm3, both: P < 0.05). Both end-diastolic and systolic measurements were available in nine arteries, showing a larger total vessel and lumen volume at systole (664 ± 221 mm3 vs. 686 ± 227 mm3, P = 0.03; 384 ± 164 mm3 vs. 393 ± 170 mm3, P = 0.08). The differences observed may be of particular interest for volumetric ICUS studies, addressing presumably small differences in vessel or lumen dimensions.
KW - Coronary artery disease
KW - Image processing
KW - Intravascular ultrasound
KW - Three-dimensional reconstruction
UR - http://www.scopus.com/inward/record.url?scp=0031888908&partnerID=8YFLogxK
U2 - 10.1002/(SICI)1097-0304(199803)43:3<254::AID-CCD3>3.0.CO;2-8
DO - 10.1002/(SICI)1097-0304(199803)43:3<254::AID-CCD3>3.0.CO;2-8
M3 - Article
C2 - 9535359
SN - 0098-6569
VL - 43
SP - 254
EP - 261
JO - Catheterization and Cardiovascular Diagnosis
JF - Catheterization and Cardiovascular Diagnosis
IS - 3
ER -
