Effectiveness of a multi-component intensive smoking cessation programme for COPD outpatients: A randomized controlled trial.

Lieke C.A. Christenhusz, Marcel E. Pieterse, Jacobus Adrianus Maria van der Palen, J. van der Palen, E.R. Seydel, P.I. van Spiegel, P.D.L.P.M. van der Valk, F.W.J.M. Smeenk

Research output: Contribution to journalArticleAcademic


Background: Chronic Obstructive Pulmonary Disease is a widespread health problem. To improve COPD prognosis the only evidence-based treatment is to quit smoking. The smoking cessation programmes available in the Netherlands are insufficient to help patients with smoking related diseases to quit. Therefore, an intensive smoking cessation programme, SmokeStopTherapy (SST), has been designed for Dutch COPD outpatients. Aim: To investigate whether the intensive SST is more effective in reducing the number of smoking outpatients with COPD compared to usual care , which is defined as the Minimal Intervention Strategy for lung patients (LMIS).Method: Patients willing to quit are randomly allocated to SST or LMIS. The SST consists of small-groups and individual counselling and pharmacological treatment (Nicotine Replacement Therapy and Bupropion). Additionally, patients can recycle in case of a relapse. Preliminary self-reported results are presented below. Results: After three months, self-reported point prevalence abstinence of 45.8% was observed for LMIS subjects (N=24), compared to 73.5% (N=34) for SST subjects ( 2 = 4.583; df =1; p<0.05).Discussion: The intensive SST seems to be significantly more effective than brief usual care intervention (LMIS), despite the low number of patients included in this preliminary analysis. Salivary cotinine-validated outcomes will be available soon.
Original languageUndefined
Pages (from-to)390s-390s
Number of pages1
JournalEuropean respiratory journal
Issue numbersuppl. 45
Publication statusPublished - 2003


  • METIS-212763
  • IR-45623

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