Electrochemical detection of electrochemically inactive cations by self-assembled monolayers of crown ethers

S. Flink; Bernard A. Boukamp; Albert van den Berg; F.C.J.M. van Veggel; David Reinhoudt

doi:10.1021/ja9734713

Electrochemical detection of electrochemically inactive cations by self-assembled monolayers of crown ethers

S. Flink, Bernard A. Boukamp, Albert van den Berg, F.C.J.M. van Veggel, David Reinhoudt

Inorganic Materials Science

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Abstract

Self-assembled monolayers (SAMs) of 2-[(6-mercaptohexyl)oxy]methyl-12-crown-4 (1) and 2-[(6-mercaptohexyl)oxy]methyl-15-crown-5 (2) on gold are able to bind cations reversibly from aqueous solutions. This binding of the electrochemically inactive cations is monitored by cyclic voltammetry and impedance spectroscopy using the redox couple Ru(NH3)62+/3+ as "reporter ion". Gold electrodes modified with 1 detect Na+ even in the presence of a 100-fold excess of K+; SAMs of 2 are K+ selective. As a result of the high surface density of crown ethers, sandwich complexes are formed. Reduced surface concentrations of receptors in mixed monolayers of 2 with heptanethiol prevent the sandwich complexation and decreases the K+/Na+ selectivity of the SAM.

Original language	Undefined
Pages (from-to)	4652-4657
Journal	Journal of the American Chemical Society
Volume	120
Issue number	120
DOIs	https://doi.org/10.1021/ja9734713
Publication status	Published - 1998

Keywords

METIS-105940
IR-10993

Access to Document

10.1021/ja9734713

Cite this

@article{0e410723dbe04fe8ad443e13bfdc7853,

title = "Electrochemical detection of electrochemically inactive cations by self-assembled monolayers of crown ethers",

abstract = "Self-assembled monolayers (SAMs) of 2-[(6-mercaptohexyl)oxy]methyl-12-crown-4 (1) and 2-[(6-mercaptohexyl)oxy]methyl-15-crown-5 (2) on gold are able to bind cations reversibly from aqueous solutions. This binding of the electrochemically inactive cations is monitored by cyclic voltammetry and impedance spectroscopy using the redox couple Ru(NH3)62+/3+ as {"}reporter ion{"}. Gold electrodes modified with 1 detect Na+ even in the presence of a 100-fold excess of K+; SAMs of 2 are K+ selective. As a result of the high surface density of crown ethers, sandwich complexes are formed. Reduced surface concentrations of receptors in mixed monolayers of 2 with heptanethiol prevent the sandwich complexation and decreases the K+/Na+ selectivity of the SAM.",

keywords = "METIS-105940, IR-10993",

author = "S. Flink and Boukamp, {Bernard A.} and {van den Berg}, Albert and {van Veggel}, F.C.J.M. and David Reinhoudt",

year = "1998",

doi = "10.1021/ja9734713",

language = "Undefined",

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pages = "4652--4657",

journal = "Journal of the American Chemical Society",

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TY - JOUR

T1 - Electrochemical detection of electrochemically inactive cations by self-assembled monolayers of crown ethers

AU - Flink, S.

AU - Boukamp, Bernard A.

AU - van den Berg, Albert

AU - van Veggel, F.C.J.M.

AU - Reinhoudt, David

PY - 1998

Y1 - 1998

N2 - Self-assembled monolayers (SAMs) of 2-[(6-mercaptohexyl)oxy]methyl-12-crown-4 (1) and 2-[(6-mercaptohexyl)oxy]methyl-15-crown-5 (2) on gold are able to bind cations reversibly from aqueous solutions. This binding of the electrochemically inactive cations is monitored by cyclic voltammetry and impedance spectroscopy using the redox couple Ru(NH3)62+/3+ as "reporter ion". Gold electrodes modified with 1 detect Na+ even in the presence of a 100-fold excess of K+; SAMs of 2 are K+ selective. As a result of the high surface density of crown ethers, sandwich complexes are formed. Reduced surface concentrations of receptors in mixed monolayers of 2 with heptanethiol prevent the sandwich complexation and decreases the K+/Na+ selectivity of the SAM.

AB - Self-assembled monolayers (SAMs) of 2-[(6-mercaptohexyl)oxy]methyl-12-crown-4 (1) and 2-[(6-mercaptohexyl)oxy]methyl-15-crown-5 (2) on gold are able to bind cations reversibly from aqueous solutions. This binding of the electrochemically inactive cations is monitored by cyclic voltammetry and impedance spectroscopy using the redox couple Ru(NH3)62+/3+ as "reporter ion". Gold electrodes modified with 1 detect Na+ even in the presence of a 100-fold excess of K+; SAMs of 2 are K+ selective. As a result of the high surface density of crown ethers, sandwich complexes are formed. Reduced surface concentrations of receptors in mixed monolayers of 2 with heptanethiol prevent the sandwich complexation and decreases the K+/Na+ selectivity of the SAM.

KW - METIS-105940

KW - IR-10993

U2 - 10.1021/ja9734713

DO - 10.1021/ja9734713

M3 - Article

SN - 0002-7863

VL - 120

SP - 4652

EP - 4657

JO - Journal of the American Chemical Society

JF - Journal of the American Chemical Society

IS - 120

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