Electrochemistry/mass spectrometry (EC/MS) - a new tool to study drug metabolism and reactio mechanisms

U. Karst

    Research output: Contribution to journalArticleAcademicpeer-review

    84 Citations (Scopus)

    Abstract

    A great combination: The coupling of electrochemistry and mass spectrometry (EC/MS) opens up new possibilities in analytics - not only in biochemistry for the investigation of natural products and metabolites, but also in the screening of combinatorial libraries and the characterization of transition-metal complexes. The mode of operation, range of application, and perspectives of the current EC/MS methods are the themes of this Highlight.
    Original languageUndefined
    Pages (from-to)2476-2478
    Number of pages3
    JournalAngewandte Chemie, International Edition in English
    Volume43
    Issue number19
    DOIs
    Publication statusPublished - 2004

    Keywords

    • Derivatization
    • METIS-222362
    • IR-72000
    • Mass spectrometry
    • Metabolism
    • Liquid Chromatography
    • Electrochemistry

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