TY - JOUR
T1 - Electroosmotic guiding of sample flows in a laminar flow chamber
AU - Besselink, Geert A.J.
AU - Vulto, Paul
AU - Lammertink, Rob G.H.
AU - Schlautmann, Stefan
AU - van den Berg, Albert
AU - Olthuis, Wouter
AU - Engbers, Gerard H.M.
AU - Schasfoort, Richard B.M.
PY - 2004
Y1 - 2004
N2 - The so-called address-flow principle is described: a valveless, electroosmotically driven technology used for controlling the stream profile in a laminar flow chamber. The method is explained, and a theoretical description and experimental verification are presented. Adjustment of the flow of two electroosmotically controlled guiding streams, running parallel to a central sample stream, can be used for positioning the sample stream in the dimension perpendicular to the flow direction. The results presented show that address-flow microfluidics allow easy and accurate control of sample stream position and width. The electroosmotic flow (EOF)-controlled guiding of microfluidic flows described in this paper, is a new unit operation that might aid in separation and collection in microfluidic devices. One possible application of addressflow microfluidics is guiding of capillary electrophoresis-separated components over a multisensor array, in order to perform affinity assays.
AB - The so-called address-flow principle is described: a valveless, electroosmotically driven technology used for controlling the stream profile in a laminar flow chamber. The method is explained, and a theoretical description and experimental verification are presented. Adjustment of the flow of two electroosmotically controlled guiding streams, running parallel to a central sample stream, can be used for positioning the sample stream in the dimension perpendicular to the flow direction. The results presented show that address-flow microfluidics allow easy and accurate control of sample stream position and width. The electroosmotic flow (EOF)-controlled guiding of microfluidic flows described in this paper, is a new unit operation that might aid in separation and collection in microfluidic devices. One possible application of addressflow microfluidics is guiding of capillary electrophoresis-separated components over a multisensor array, in order to perform affinity assays.
KW - Micro-fabrication
KW - Miniaturization
KW - Address flow
KW - Micro-fluidics
KW - Electro-osmotic flow
U2 - 10.1002/elps.200406033
DO - 10.1002/elps.200406033
M3 - Article
SN - 0173-0835
VL - 25
SP - 3705
EP - 3711
JO - Electrophoresis
JF - Electrophoresis
IS - 21-22
ER -