Electrospinning: A Fast Process for Imprinting Micro and Nano Patterns on Electrospun Fiber Meshes at Physiological Temperatures

Anandkumar Nandakumar; Roman Truckenmüller; Maqsood Ahmed; Febriyani Damanik; Diogo Reis Santos; Nils Auffermann; Jan de Boer; Pamela Habibovic; Clemens van Blitterswijk; Lorenzo Moroni

doi:10.1002/smll.201300220

Electrospinning: A Fast Process for Imprinting Micro and Nano Patterns on Electrospun Fiber Meshes at Physiological Temperatures

Anandkumar Nandakumar, Roman Truckenmüller, Maqsood Ahmed, Febriyani Damanik, Diogo Reis Santos, Nils Auffermann, Jan de Boer, Pamela Habibovic, Clemens van Blitterswijk, Lorenzo Moroni^*

^*Corresponding author for this work

Faculty of Science and Technology

Research output: Contribution to journal › Article › Academic › peer-review

42 Citations (Scopus)

Abstract

Electrospun fiber meshes are patterned at length scales comparable to or lower than their fiber diameter. Simple nano- and microgrooves and closed geometric shapes are imprinted in different tones using a fast imprint process at physiological temperatures. Human mesenchymal stromal cells cultured on patterned scaffolds show differences in cellular morphology and cytoskeleton organization. Microgrooved electrospun fibers support upregulation of alkaline phosphatase and bone morphogenetic protein-2 gene expression when cells are cultured in osteogenic medium.

Original language	English
Pages (from-to)	3405-3409
Journal	Small
Volume	9
Issue number	20
DOIs	https://doi.org/10.1002/smll.201300220
Publication status	Published - 27 Feb 2013

Keywords

n/a OA procedure

Access to Document

10.1002/smll.201300220

Cite this

@article{c7e9733233e84c66ab976ddb608fe1aa,

title = "Electrospinning: A Fast Process for Imprinting Micro and Nano Patterns on Electrospun Fiber Meshes at Physiological Temperatures",

abstract = "Electrospun fiber meshes are patterned at length scales comparable to or lower than their fiber diameter. Simple nano- and microgrooves and closed geometric shapes are imprinted in different tones using a fast imprint process at physiological temperatures. Human mesenchymal stromal cells cultured on patterned scaffolds show differences in cellular morphology and cytoskeleton organization. Microgrooved electrospun fibers support upregulation of alkaline phosphatase and bone morphogenetic protein-2 gene expression when cells are cultured in osteogenic medium.",

keywords = "n/a OA procedure",

author = "Anandkumar Nandakumar and Roman Truckenm{\"u}ller and Maqsood Ahmed and Febriyani Damanik and Santos, {Diogo Reis} and Nils Auffermann and {de Boer}, Jan and Pamela Habibovic and {van Blitterswijk}, Clemens and Lorenzo Moroni",

year = "2013",

month = feb,

day = "27",

doi = "10.1002/smll.201300220",

language = "English",

volume = "9",

pages = "3405--3409",

journal = "Small",

issn = "1613-6810",

publisher = "Wiley-VCH Verlag",

number = "20",

}

TY - JOUR

T1 - Electrospinning

T2 - A Fast Process for Imprinting Micro and Nano Patterns on Electrospun Fiber Meshes at Physiological Temperatures

AU - Nandakumar, Anandkumar

AU - Truckenmüller, Roman

AU - Ahmed, Maqsood

AU - Damanik, Febriyani

AU - Santos, Diogo Reis

AU - Auffermann, Nils

AU - de Boer, Jan

AU - Habibovic, Pamela

AU - van Blitterswijk, Clemens

AU - Moroni, Lorenzo

PY - 2013/2/27

Y1 - 2013/2/27

N2 - Electrospun fiber meshes are patterned at length scales comparable to or lower than their fiber diameter. Simple nano- and microgrooves and closed geometric shapes are imprinted in different tones using a fast imprint process at physiological temperatures. Human mesenchymal stromal cells cultured on patterned scaffolds show differences in cellular morphology and cytoskeleton organization. Microgrooved electrospun fibers support upregulation of alkaline phosphatase and bone morphogenetic protein-2 gene expression when cells are cultured in osteogenic medium.

AB - Electrospun fiber meshes are patterned at length scales comparable to or lower than their fiber diameter. Simple nano- and microgrooves and closed geometric shapes are imprinted in different tones using a fast imprint process at physiological temperatures. Human mesenchymal stromal cells cultured on patterned scaffolds show differences in cellular morphology and cytoskeleton organization. Microgrooved electrospun fibers support upregulation of alkaline phosphatase and bone morphogenetic protein-2 gene expression when cells are cultured in osteogenic medium.

KW - n/a OA procedure

U2 - 10.1002/smll.201300220

DO - 10.1002/smll.201300220

M3 - Article

SN - 1613-6810

VL - 9

SP - 3405

EP - 3409

JO - Small

JF - Small

IS - 20

ER -