Encapsulation of phthalocyanine supramolecular stacks into virus-like particles

M. Brasch, Andrés de la Escosura, Y. Ma, Charlotte Uetrecht, Albert J.R. Heck, Tomás Torres, Jeroen Johannes Lambertus Maria Cornelissen

Research output: Contribution to journalArticleAcademicpeer-review

112 Citations (Scopus)

Abstract

We report herein the encapsulation of a water-soluble phthalocyanine (Pc) into virus-like particles (VLPs) of two different sizes, depending on the conditions. At neutral pH, the cooperative encapsulation/templated assembly of the particles induces the formation of Pc stacks instead of Pc dimers, due to an increased confinement concentration. The Pc-containing VLPs may potentially be used as photosensitizer/vehicle systems for biomedical applications such as photodynamic therapy
Original languageEnglish
Pages (from-to)6878-6881
Number of pages3
JournalJournal of the American Chemical Society
Volume133
Issue number18
DOIs
Publication statusPublished - 2011

Keywords

  • METIS-283465
  • IR-104433

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