Abstract
Purpose: To evaluate the feasibility and safety of endovenous mechanochemical ablation (MOCA) for the treatment of great saphenous vein (GSV) incompetence. Methods: The newly developed ClariVein device uses a technique that combines mechanical endothelial damage using a rotating wire with the infusion of a liquid sclerosant. Heating of the vein and tumescent anesthesia are not required; only local anesthesia is utilized at the insertion site. In a pilot study, 30 limbs in 25 patients (18 women; mean age 52 years) with GSV incompetence were treated with MOCA using polidocanol at 2 centers. Initial technical success, complications, patient satisfaction, and classification by venous clinical severity score (VCSS) were assessed 6 weeks after the treatment. Results: Initial technical success of MOCA was 100%. There were no major adverse events. Minor complications consisted of 9 local ecchymoses at the puncture site and superficial phlebitis that resolved within a week in 4 limbs. Duplex ultrasonography at 6 weeks showed 26 (87%) of 30 veins were completely occluded; 3 veins showed partial recanalization in the proximal (n=2) and distal GSV. One patient had full segment recanalization and was successfully retreated. The VCSS significantly improved at 6 weeks (p<0.001). Patient satisfaction was high, with a median satisfaction of 8.8 on a 0-10 scale. Conclusion: This study showed that endovenous MOCA, using polidocanol, is feasible and safe in the treatment of GSV incompetence. Larger studies with a prolonged follow-up are indicated to prove the efficacy of this technique in terms of obliteration rates.
Original language | English |
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Pages (from-to) | 328-334 |
Number of pages | 7 |
Journal | Journal of Endovascular Therapy |
Volume | 18 |
Issue number | 3 |
DOIs | |
Publication status | Published - 1 Jun 2011 |
Externally published | Yes |
Keywords
- Endovenous ablation
- Endovenous therapy
- Great saphenous vein
- Mechanical endothelial damage
- Polidocanol
- Sclerosant
- Varicose veins
- Venous incompetence