Engineered Micro-Objects as Scaffolding Elements in Cellular Building Blocks for Bottom-Up Tissue Engineering Approaches

Anne Marijke Leferink, D. Schipper, E. Arts, E.J. Vrij, N.C. Rivron, Hermanus Bernardus Johannes Karperien, K. Mittmann, Clemens van Blitterswijk, Lorenzo Moroni, R.K. Truckenmüller

Research output: Contribution to journalArticleAcademicpeer-review

32 Citations (Scopus)

Abstract

A material-based bottom-up approach is proposed towards an assembly of cells and engineered micro-objects at the macroscale. We show how shape, size and wettability of engineered micro-objects play an important role in the behavior of cells on these objects. This approach can, among other applications, be used as a tool to engineer complex 3D tissues of clinically relevant size.
Original languageEnglish
Pages (from-to)2592-2599
JournalAdvanced materials
Volume26
Issue number16
DOIs
Publication statusPublished - 7 Jan 2014

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Tissue engineering
Wetting
Cells
Tissue
Engineers

Keywords

  • METIS-299945
  • IR-88436

Cite this

Leferink, Anne Marijke ; Schipper, D. ; Arts, E. ; Vrij, E.J. ; Rivron, N.C. ; Karperien, Hermanus Bernardus Johannes ; Mittmann, K. ; van Blitterswijk, Clemens ; Moroni, Lorenzo ; Truckenmüller, R.K. / Engineered Micro-Objects as Scaffolding Elements in Cellular Building Blocks for Bottom-Up Tissue Engineering Approaches. In: Advanced materials. 2014 ; Vol. 26, No. 16. pp. 2592-2599.
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Leferink, AM, Schipper, D, Arts, E, Vrij, EJ, Rivron, NC, Karperien, HBJ, Mittmann, K, van Blitterswijk, C, Moroni, L & Truckenmüller, RK 2014, 'Engineered Micro-Objects as Scaffolding Elements in Cellular Building Blocks for Bottom-Up Tissue Engineering Approaches' Advanced materials, vol. 26, no. 16, pp. 2592-2599. https://doi.org/10.1002/adma.201304539

Engineered Micro-Objects as Scaffolding Elements in Cellular Building Blocks for Bottom-Up Tissue Engineering Approaches. / Leferink, Anne Marijke; Schipper, D.; Arts, E.; Vrij, E.J.; Rivron, N.C.; Karperien, Hermanus Bernardus Johannes; Mittmann, K.; van Blitterswijk, Clemens; Moroni, Lorenzo; Truckenmüller, R.K.

In: Advanced materials, Vol. 26, No. 16, 07.01.2014, p. 2592-2599.

Research output: Contribution to journalArticleAcademicpeer-review

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