Enhancement of NMR sensitivity in nanoliter samples by dynamic nuclear polarization and microcoils fabricated on capillaries by shadow mask lithography

Piotr Kurek*, Gijs Van Der Heijden, Jan Van Bentum, Arno Kentgens, Han Gardeniers

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

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Abstract

Modern dynamic nuclear polarization (DNP) systems produce a high nuclear magnetic resonance (NMR) signal enhancement but distort the static magnetic field in an NMR system. As a result the obtained spectrum has a resolution not suitable for most NMR applications. Localizing the detection region only to the part of the resonator where the magnetic field component of microwave (MW) is the highest and highest static magnetic field homogeneity should increase the resolution without compromising enhancement. Here we present a novel method of manufacturing a microcoil on a capillary, enabling localized in-situ NMR detection inside a MW cavity.

Original languageEnglish
Title of host publicationProceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012
PublisherThe Chemical and Biological Microsystems Society
Pages1354-1356
Number of pages3
ISBN (Print)9780979806452
Publication statusPublished - 2012
Event16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2012 - Okinawa, Japan
Duration: 28 Oct 20121 Nov 2012
Conference number: 16

Conference

Conference16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2012
Abbreviated titleMicroTAS
Country/TerritoryJapan
CityOkinawa
Period28/10/121/11/12

Keywords

  • Dynamic nuclear polarization
  • Microcoil
  • Nuclear magnetic resonance

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