Ernstig parkinsonisme ten gevolge van metoclopramide bij een patiënte met polyfarmacie

A. Hoogendam; J. Hofmeijer; C. J.M. Frijns; M. Heeringa; S. L.N.M. Schouten-Tjin A Tsoi; P. A.F. Jansen

Ernstig parkinsonisme ten gevolge van metoclopramide bij een patiënte met polyfarmacie

Translated title of the contribution: Severe parkinsonism as a consequence of metoclopramide use in a patient with polypharmacy

A. Hoogendam^*
, J. Hofmeijer
, C. J.M. Frijns
, M. Heeringa
, S. L.N.M. Schouten-Tjin A Tsoi
, P. A.F. Jansen

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

3 Citations (Scopus)

74 Downloads (Pure)

Abstract

A 73-year-old woman, with tuberculosis of the large intestine, developed nausea as a side effect of the antituberculosis drugs. The nausea was treated with metoclopramide. Subsequently she developed severe medication-induced parkinsonism. As her symptoms initially mimicked a depressive disorder, drug-induced parkinsonism was only considered at a later stage. Due to drug-induced impaired function of the liver and kidney the patient had received a toxic dose of metoclopramide. Treatment with biperiden and withdrawal of the metoclopramide resulted in a reduction of the complaints within 3 months, after which the anti-tuberculosis medication could be reintroduced. Adjusting the dose of metoclopramide could possibly have prevented this severe side effect.

Translated title of the contribution	Severe parkinsonism as a consequence of metoclopramide use in a patient with polypharmacy
Original language	Dutch
Pages (from-to)	175-177
Number of pages	3
Journal	Nederlands tijdschrift voor geneeskunde
Volume	146
Issue number	4
Publication status	Published - 26 Jan 2002

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

22/3 OA procedure

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2002101750001aFinal published version, 81 KBLicence: Taverne

https://www.ntvg.nl/artikelen/ernstig-parkinsonisme-ten-gevolge-van-metoclopramide-bij-een-patiente-met-polyfarmacie

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Hoogendam, A., Hofmeijer, J., Frijns, C. J. M., Heeringa, M., Schouten-Tjin A Tsoi, S. L. N. M., & Jansen, P. A. F. (2002). Ernstig parkinsonisme ten gevolge van metoclopramide bij een patiënte met polyfarmacie. Nederlands tijdschrift voor geneeskunde, 146(4), 175-177. https://www.ntvg.nl/artikelen/ernstig-parkinsonisme-ten-gevolge-van-metoclopramide-bij-een-patiente-met-polyfarmacie

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title = "Ernstig parkinsonisme ten gevolge van metoclopramide bij een pati{\"e}nte met polyfarmacie",

abstract = "A 73-year-old woman, with tuberculosis of the large intestine, developed nausea as a side effect of the antituberculosis drugs. The nausea was treated with metoclopramide. Subsequently she developed severe medication-induced parkinsonism. As her symptoms initially mimicked a depressive disorder, drug-induced parkinsonism was only considered at a later stage. Due to drug-induced impaired function of the liver and kidney the patient had received a toxic dose of metoclopramide. Treatment with biperiden and withdrawal of the metoclopramide resulted in a reduction of the complaints within 3 months, after which the anti-tuberculosis medication could be reintroduced. Adjusting the dose of metoclopramide could possibly have prevented this severe side effect.",

keywords = "22/3 OA procedure",

author = "A. Hoogendam and J. Hofmeijer and Frijns, \{C. J.M.\} and M. Heeringa and \{Schouten-Tjin A Tsoi\}, \{S. L.N.M.\} and Jansen, \{P. A.F.\}",

year = "2002",

month = jan,

day = "26",

language = "Dutch",

volume = "146",

pages = "175--177",

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Hoogendam, A, Hofmeijer, J, Frijns, CJM, Heeringa, M, Schouten-Tjin A Tsoi, SLNM & Jansen, PAF 2002, 'Ernstig parkinsonisme ten gevolge van metoclopramide bij een patiënte met polyfarmacie', Nederlands tijdschrift voor geneeskunde, vol. 146, no. 4, pp. 175-177. <https://www.ntvg.nl/artikelen/ernstig-parkinsonisme-ten-gevolge-van-metoclopramide-bij-een-patiente-met-polyfarmacie>

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T1 - Ernstig parkinsonisme ten gevolge van metoclopramide bij een patiënte met polyfarmacie

AU - Hoogendam, A.

AU - Hofmeijer, J.

AU - Frijns, C. J.M.

AU - Heeringa, M.

AU - Schouten-Tjin A Tsoi, S. L.N.M.

AU - Jansen, P. A.F.

PY - 2002/1/26

Y1 - 2002/1/26

N2 - A 73-year-old woman, with tuberculosis of the large intestine, developed nausea as a side effect of the antituberculosis drugs. The nausea was treated with metoclopramide. Subsequently she developed severe medication-induced parkinsonism. As her symptoms initially mimicked a depressive disorder, drug-induced parkinsonism was only considered at a later stage. Due to drug-induced impaired function of the liver and kidney the patient had received a toxic dose of metoclopramide. Treatment with biperiden and withdrawal of the metoclopramide resulted in a reduction of the complaints within 3 months, after which the anti-tuberculosis medication could be reintroduced. Adjusting the dose of metoclopramide could possibly have prevented this severe side effect.

AB - A 73-year-old woman, with tuberculosis of the large intestine, developed nausea as a side effect of the antituberculosis drugs. The nausea was treated with metoclopramide. Subsequently she developed severe medication-induced parkinsonism. As her symptoms initially mimicked a depressive disorder, drug-induced parkinsonism was only considered at a later stage. Due to drug-induced impaired function of the liver and kidney the patient had received a toxic dose of metoclopramide. Treatment with biperiden and withdrawal of the metoclopramide resulted in a reduction of the complaints within 3 months, after which the anti-tuberculosis medication could be reintroduced. Adjusting the dose of metoclopramide could possibly have prevented this severe side effect.

KW - 22/3 OA procedure

UR - https://www.scopus.com/pages/publications/0037176492

M3 - Article

C2 - 11845569

AN - SCOPUS:0037176492

SN - 0028-2162

VL - 146

SP - 175

EP - 177

JO - Nederlands tijdschrift voor geneeskunde

JF - Nederlands tijdschrift voor geneeskunde

IS - 4

ER -

Ernstig parkinsonisme ten gevolge van metoclopramide bij een patiënte met polyfarmacie

Abstract

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