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Research output per year
Edzo M.E. Klawer, Petra J. van Houdt, Frank F.J. Simonis, Cornelis A.T. van den Berg, Floris J. Pos, Stijn W.T.P.J. Heijmink, Sofie Isebaert, Karin Haustermans, Uulke A. van der Heide*
Research output: Contribution to journal › Comment/Letter to the editor › Academic › peer-review
The antilog for the within-subject coefficient of variation (wCV) of log-transformed data was performed incorrectly. This leads to an increase by a factor of about 2 in the numbers in abstract, results section, Figure 4, Tables 2 and 3. Although this affected all wCV values reported in the manuscript, the conclusion remains the same. The authors regret this mistake and apologize for any inconvenience this may have caused. 4 FIGURE (Figure presented.) Bar plot of wCV values for Ktrans and kep for the three AIF methods including 95% CI bars 2 TABLE Median, range and wCV with 95% confidence interval of the AIF curve characteristics between the two consecutive exams (Table presented.) 3 TABLE The wCV between left and right AIFs, per method (magnitude, phase and complex signal), with 95% confidence interval for all curve characteristics (Table presented.) Abstract (changes in wCV values): Results: The wCV for peak height and full-width at half maximum for AIFCOMPLEX (15% and 17%) indicated an improved repeatability compared to AIFMAGN (28% and 26%) and AIFPHASE (27% and 16%). This translated in lower wCV values for Ktrans (24%) with AIFCOMPLEX in comparison to AIFMAGN (52%) and AIFPHASE (32%). For kep the wCV was 35% with AIFMAGN, 29% with AIFPHASE, and 29% with AIFCOMPLEX. Results section, “3.2 AIF curve characteristics per method”, P6 (changes in numbers): Without a B1 correction, the peak height ratio for AIFMAGN increased to 1.5, whereas the wCV increased from 33 to 43%. Results section, “3. Tracer kinetic analysis”, P6 (changes in p-values): The wCV for Ktrans obtained with AIFMAGN was significantly larger than for the other two methods (p = 0.0026 and < 0.001 for AIFPHASE and AIFCOMPLEX respectively), however, for kep the wCV were not significantly larger (p = 0.59 and 0.63 for AIFPHASE and AIFCOMPLEX respectively). Discussion, P9 (the word “higher” becomes “similar”): However, in general the reported wCV of Ktrans in ROIs is similar than what we observe for Ktrans obtained with AIFCOMPLEX: range between 12.5% to 57%.46-50.
Research output: Contribution to journal › Article › Academic › peer-review