Evaluation of cardiac modulation in children in response to apnea/hypopnea using the Phone Oximeter™

Parastoo Dehkordi, Ainara Garde, Walter Karlen, Christian L. Petersen, David Wensley, Guy A. Dumont, J. Mark Ansermino

Research output: Contribution to journalArticleAcademicpeer-review

16 Citations (Scopus)


Individuals with sleep disordered breathing (SDB) can experience changes in automatic cardiac regulation as a result of frequent sleep fragmentation and disturbance in normal respiration and oxygenation that accompany most apnea/hypopnea events. In adults, these changes are reflected in enhanced sympathetic and reduced parasympathetic activity. In this study, we examined the autonomic cardiac regulation in children with and without SDB, through spectral and detrended fluctuation analysis (DFA) of pulse rate variability (PRV). PRV was measured from pulse-to-pulse intervals (PPIs) of the photoplethysmogram (PPG) recorded from 160 children using the Phone Oximeter ™ in the standard setting of overnight polysomnography. Spectral analysis of PRV showed the cardiac parasympathetic index (high frequency, HF) was lower ( p
Original languageEnglish
Pages (from-to)187-202
Number of pages16
JournalPhysiological measurement
Issue number2
Publication statusPublished - 5 Jan 2016
Externally publishedYes


  • apnea/hypopnea
  • mobile health
  • phone oximeter
  • photoplethysmogram
  • pulse rate variability
  • sleep disordered breathing


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