Evaluation of Electrocardiogram-Gated Computed Tomography Angiography to Quantify Changes in Geometry and Dynamic Behavior during the Cardiac Cycle of the Nellix Endovascular Sealing System

Leo H. Van Den Ham, Talar Lazarian, Erik Groot Jebbink, Jan-Willem H.P. Lardenoije, Clark J. Zeebregts, Michel M. P. J. Reijnen*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

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Abstract

Background. The Nellix endovascular sealing system (EVAS) was a unique concept with regard to its sealing concept that failed, related to high migration rates. We investigated the changes in aortoiliac morphology during the cardiac cycle before and after EVAS using electrocardiography (ECG)-gated CT. Methods. Eight patients scheduled for EVAS were prospectively enrolled. ECG-gated CT scans were made pre- and postoperatively. Measurements were performed in the mid-systolic and mid-diastolic phases. Endpoints were changes in infrarenal aortoiliac morphology postoperatively compared to preoperatively and their changes in the cardiac cycle. Results. Both pre- and postoperatively, there were no changes during the cardiac cycle. EVAS caused an increase in neck diameter and surface in both phases (). EVAS increased the luminal AAA volume (), with a decrease in thrombus volume () in both phases and an increase in total volume () in the systolic phase. During follow-up, one patient presented with >5 mm migration. There were no differences in the movements of this patient compared to the remaining patients. Conclusion. The cardiac cycle had a very limited effect on the aortoiliac dynamics before and after EVAS and, therefore, there is probably not a role for ECG-gated CT in enhanced surveillance programs. EVAS itself has a significant impact on anatomy, particularly the neck diameter, length, and volumes of the AAA.
Original languageEnglish
Article number3721185
JournalRadiology Research and Practice
Volume2023
DOIs
Publication statusPublished - 21 Jun 2023

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