Evaluation of peristaltic micromixers for highly integrated microfluidic systems

Duckjong Kim, Hoon Suk Rho, Sachin Jambovane, Soojeong Shin, Jong Wook Hong*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

2 Citations (Scopus)
70 Downloads (Pure)

Abstract

Microfluidic devices based on the multilayer soft lithography allow accurate manipulation of liquids, handling reagents at the sub-nanoliter level, and performing multiple reactions in parallel processors by adapting micromixers. Here, we have experimentally evaluated and compared several designs of micromixers and operating conditions to find design guidelines for the micromixers. We tested circular, triangular, and rectangular mixing loops and measured mixing performance according to the position and the width of the valves that drive nanoliters of fluids in the micrometer scale mixing loop. We found that the rectangular mixer is best for the applications of highly integrated microfluidic platforms in terms of the mixing performance and the space utilization. This study provides an improved understanding of the flow behaviors inside micromixers and design guidelines for micromixers that are critical to build higher order fluidic systems for the complicated parallel bio/chemical processes on a chip.

Original languageEnglish
Article number035003
JournalReview of scientific instruments
Volume87
Issue number3
DOIs
Publication statusPublished - 1 Mar 2016

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