Evanescent wave sensing: new features for detection in small volumes

G. Pandraud, T.M. Koster, C. Gui, M. Dijkstra, A. van den Berg, P. Lambeck

Research output: Contribution to journalArticleAcademicpeer-review

52 Citations (Scopus)


The association by aligned direct bonding of an evanescent wave optical sensor and small-volume flow cells for visible absorption detection is demonstrated. We show that for sample volumes ranging from 760 to 190 nl and a sensor interaction length of 1 mm, very small cross-sectional dimensions of fluid channels are no more a serious obstacle for optical detection. The lowest limit for the channel depth is the penetration depth of the
Original languageEnglish
Pages (from-to)158-162
Number of pages5
JournalSensors and actuators. A: Physical
Issue number1-3
Publication statusPublished - 2000


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