TY - JOUR
T1 - Experimental myringoplasty
AU - Feenstra, L.
AU - Van Der Ven, B. W.C.
AU - Kohn, F. E.
AU - Feijen, J.
PY - 1980/12/1
Y1 - 1980/12/1
N2 - Artificial eardrums made from biodegradable poly(D,L-lactic acid), poly(glycolic acid) and poly(β-benzyl-L-aspartate-co-L-leucine) 50/50, and made from the microporous poly(tetrafluoroethylene) and bisphenol-A poly(carbonate) membranes were implanted into the ear and as a refernce subcutaneously in rats. The implants were histologically examined for periods up to one year. From the biodegradable polymers studied the poly(β-benzyl-L-aspartate-co-L-leucine) 50/50 evoked the least tissue reaction and the newly formed tympanic membranes are the best in terms of thickness and overall integrity. The microporous poly(tetrafluoroethylene) membrane can be considered as a valuable support for the formation of a reinforced tympanic membrane.
AB - Artificial eardrums made from biodegradable poly(D,L-lactic acid), poly(glycolic acid) and poly(β-benzyl-L-aspartate-co-L-leucine) 50/50, and made from the microporous poly(tetrafluoroethylene) and bisphenol-A poly(carbonate) membranes were implanted into the ear and as a refernce subcutaneously in rats. The implants were histologically examined for periods up to one year. From the biodegradable polymers studied the poly(β-benzyl-L-aspartate-co-L-leucine) 50/50 evoked the least tissue reaction and the newly formed tympanic membranes are the best in terms of thickness and overall integrity. The microporous poly(tetrafluoroethylene) membrane can be considered as a valuable support for the formation of a reinforced tympanic membrane.
UR - http://www.scopus.com/inward/record.url?scp=0019292888&partnerID=8YFLogxK
U2 - 10.1177/039139888000300612
DO - 10.1177/039139888000300612
M3 - Article
C2 - 6257616
AN - SCOPUS:0019292888
SN - 0391-3988
VL - 3
SP - 354
EP - 357
JO - The International journal of artificial organs
JF - The International journal of artificial organs
IS - 6
ER -