Experimental myringoplasty

L. Feenstra*, R. Baarsma, J. Feijen, H.J. Houthoff

*Corresponding author for this work

    Research output: Contribution to journalArticleAcademicpeer-review

    1 Citation (Scopus)


    Different materials were compared as implants in performing a myringoplasty on rats immediately after making a total perforation, (autologous fascia, homologous tympanic membrane, homologous collagen, heterologous collagen, heterologous amnion and proplast). As a reference one group of rats had no myringoplasty done after perforating their drums. The animals were examined regularly, then killed after 40 and 64 weeks. Macroscopically and microscopically proplast and homologous collagen were very inferior to homograft tympanic membrane and autologous fascia. The best results were obtained both macroscopically and histologically with heterologous collagen and heterologous amnion.

    Original languageEnglish
    Pages (from-to)251-257
    Number of pages7
    JournalJournal of Bioengineering
    Issue number3-4
    Publication statusPublished - 1 Jun 1978


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