Experimental myringoplasty

L. Feenstra; B.W.C. van der Ven; F.E. Kohn; J. Feijen

doi:10.1177/039139888000300612

Experimental myringoplasty

L. Feenstra
, B.W.C. van der Ven
, F.E. Kohn
, J. Feijen

University of Twente

Research output: Contribution to journal › Article › Academic › peer-review

5 Citations (Scopus)

Abstract

Artificial eardrums made from biodegradable poly(D,L-lactic acid), poly(glycolic acid) and poly(β-benzyl-L-aspartate-co-L-leucine) 50/50, and made from the microporous poly(tetrafluoroethylene) and bisphenol-A poly(carbonate) membranes were implanted into the ear and as a refernce subcutaneously in rats. The implants were histologically examined for periods up to one year. From the biodegradable polymers studied the poly(β-benzyl-L-aspartate-co-L-leucine) 50/50 evoked the least tissue reaction and the newly formed tympanic membranes are the best in terms of thickness and overall integrity. The microporous poly(tetrafluoroethylene) membrane can be considered as a valuable support for the formation of a reinforced tympanic membrane.

Original language	English
Pages (from-to)	354-357
Number of pages	4
Journal	The International journal of artificial organs
Volume	3
Issue number	6
DOIs	https://doi.org/10.1177/039139888000300612
Publication status	Published - 1 Dec 1980

Keywords

n/a OA procedure

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10.1177/039139888000300612

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title = "Experimental myringoplasty",

abstract = "Artificial eardrums made from biodegradable poly(D,L-lactic acid), poly(glycolic acid) and poly(β-benzyl-L-aspartate-co-L-leucine) 50/50, and made from the microporous poly(tetrafluoroethylene) and bisphenol-A poly(carbonate) membranes were implanted into the ear and as a refernce subcutaneously in rats. The implants were histologically examined for periods up to one year. From the biodegradable polymers studied the poly(β-benzyl-L-aspartate-co-L-leucine) 50/50 evoked the least tissue reaction and the newly formed tympanic membranes are the best in terms of thickness and overall integrity. The microporous poly(tetrafluoroethylene) membrane can be considered as a valuable support for the formation of a reinforced tympanic membrane.",

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TY - JOUR

T1 - Experimental myringoplasty

AU - Feenstra, L.

AU - van der Ven, B.W.C.

AU - Kohn, F.E.

AU - Feijen, J.

PY - 1980/12/1

Y1 - 1980/12/1

N2 - Artificial eardrums made from biodegradable poly(D,L-lactic acid), poly(glycolic acid) and poly(β-benzyl-L-aspartate-co-L-leucine) 50/50, and made from the microporous poly(tetrafluoroethylene) and bisphenol-A poly(carbonate) membranes were implanted into the ear and as a refernce subcutaneously in rats. The implants were histologically examined for periods up to one year. From the biodegradable polymers studied the poly(β-benzyl-L-aspartate-co-L-leucine) 50/50 evoked the least tissue reaction and the newly formed tympanic membranes are the best in terms of thickness and overall integrity. The microporous poly(tetrafluoroethylene) membrane can be considered as a valuable support for the formation of a reinforced tympanic membrane.

AB - Artificial eardrums made from biodegradable poly(D,L-lactic acid), poly(glycolic acid) and poly(β-benzyl-L-aspartate-co-L-leucine) 50/50, and made from the microporous poly(tetrafluoroethylene) and bisphenol-A poly(carbonate) membranes were implanted into the ear and as a refernce subcutaneously in rats. The implants were histologically examined for periods up to one year. From the biodegradable polymers studied the poly(β-benzyl-L-aspartate-co-L-leucine) 50/50 evoked the least tissue reaction and the newly formed tympanic membranes are the best in terms of thickness and overall integrity. The microporous poly(tetrafluoroethylene) membrane can be considered as a valuable support for the formation of a reinforced tympanic membrane.

KW - n/a OA procedure

UR - https://www.scopus.com/pages/publications/0019292888

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DO - 10.1177/039139888000300612

M3 - Article

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VL - 3

SP - 354

EP - 357

JO - The International journal of artificial organs

JF - The International journal of artificial organs

IS - 6

ER -

Experimental myringoplasty

Abstract

Keywords

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