Experimental Study of the depth influence on the band broadening effect in a cyclo-olefin polymer column containing an array of ordered pillars

Xavi Illa, Wim de Malsche, Johannes G.E. Gardeniers, Gert Desmet, Albert Romano-Rodriguez

Research output: Contribution to journalArticleAcademicpeer-review

12 Citations (Scopus)

Abstract

An experimental study of a micromachined non-porous pillar array column performance under non-retentive conditions is presented. The same pillar structure has been fabricated in cyclo-olefin polymer (COP) chips with three different depths via hot embossing and pressure-assisted thermal bonding. The influence of the depth on the band broadening along with the already known contribution arising from the top and bottom cover plates has been studied. The experimental results exhibit reduced plate heights as low as 0.2, which are in agreement with the previous experimental work. Moreover, the constant values of the reduced Van Deemter expression are also in accordance with the previous studies. A more exhaustive study of the C-term band broadening is also presented, showing that comparing the space between the pillars with different open tubular rectangular channels offers a good estimation of the C-term band broadening that is obtained experimentally. These experimental results, hence, confirm that micromachined pillar array columns fabricated in COP can achieve the same performance as the ones fabricated in silicon for the presently studied pillar channel design
Original languageEnglish
Pages (from-to)5817-5821
Number of pages5
JournalJournal of chromatography A
Volume1217
Issue number37
DOIs
Publication statusPublished - 2010

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Alkenes
Polymers
Silicon
Hot Temperature
Pressure

Keywords

  • METIS-268490
  • IR-94214

Cite this

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title = "Experimental Study of the depth influence on the band broadening effect in a cyclo-olefin polymer column containing an array of ordered pillars",
abstract = "An experimental study of a micromachined non-porous pillar array column performance under non-retentive conditions is presented. The same pillar structure has been fabricated in cyclo-olefin polymer (COP) chips with three different depths via hot embossing and pressure-assisted thermal bonding. The influence of the depth on the band broadening along with the already known contribution arising from the top and bottom cover plates has been studied. The experimental results exhibit reduced plate heights as low as 0.2, which are in agreement with the previous experimental work. Moreover, the constant values of the reduced Van Deemter expression are also in accordance with the previous studies. A more exhaustive study of the C-term band broadening is also presented, showing that comparing the space between the pillars with different open tubular rectangular channels offers a good estimation of the C-term band broadening that is obtained experimentally. These experimental results, hence, confirm that micromachined pillar array columns fabricated in COP can achieve the same performance as the ones fabricated in silicon for the presently studied pillar channel design",
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Experimental Study of the depth influence on the band broadening effect in a cyclo-olefin polymer column containing an array of ordered pillars. / Illa, Xavi; de Malsche, Wim; Gardeniers, Johannes G.E.; Desmet, Gert; Romano-Rodriguez, Albert.

In: Journal of chromatography A, Vol. 1217, No. 37, 2010, p. 5817-5821.

Research output: Contribution to journalArticleAcademicpeer-review

TY - JOUR

T1 - Experimental Study of the depth influence on the band broadening effect in a cyclo-olefin polymer column containing an array of ordered pillars

AU - Illa, Xavi

AU - de Malsche, Wim

AU - Gardeniers, Johannes G.E.

AU - Desmet, Gert

AU - Romano-Rodriguez, Albert

PY - 2010

Y1 - 2010

N2 - An experimental study of a micromachined non-porous pillar array column performance under non-retentive conditions is presented. The same pillar structure has been fabricated in cyclo-olefin polymer (COP) chips with three different depths via hot embossing and pressure-assisted thermal bonding. The influence of the depth on the band broadening along with the already known contribution arising from the top and bottom cover plates has been studied. The experimental results exhibit reduced plate heights as low as 0.2, which are in agreement with the previous experimental work. Moreover, the constant values of the reduced Van Deemter expression are also in accordance with the previous studies. A more exhaustive study of the C-term band broadening is also presented, showing that comparing the space between the pillars with different open tubular rectangular channels offers a good estimation of the C-term band broadening that is obtained experimentally. These experimental results, hence, confirm that micromachined pillar array columns fabricated in COP can achieve the same performance as the ones fabricated in silicon for the presently studied pillar channel design

AB - An experimental study of a micromachined non-porous pillar array column performance under non-retentive conditions is presented. The same pillar structure has been fabricated in cyclo-olefin polymer (COP) chips with three different depths via hot embossing and pressure-assisted thermal bonding. The influence of the depth on the band broadening along with the already known contribution arising from the top and bottom cover plates has been studied. The experimental results exhibit reduced plate heights as low as 0.2, which are in agreement with the previous experimental work. Moreover, the constant values of the reduced Van Deemter expression are also in accordance with the previous studies. A more exhaustive study of the C-term band broadening is also presented, showing that comparing the space between the pillars with different open tubular rectangular channels offers a good estimation of the C-term band broadening that is obtained experimentally. These experimental results, hence, confirm that micromachined pillar array columns fabricated in COP can achieve the same performance as the ones fabricated in silicon for the presently studied pillar channel design

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KW - IR-94214

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