Explosive onset of continuous wave laser tissue ablation

R. M. Verdaasdonk*, C. Borst, M. J.C. Van Gemert

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

51 Citations (Scopus)
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Abstract

The phenomena at the onset of and during tissue ablation using continuous wave lasers were studied. Aortic and myocardial bovine tissues were exposed in air and in water to Nd-YAG (10 to 60 W) and argon (3.5 W) laser light. The transmitted light was measured, the surface of the tissue was filmed and the tissue was processed for histology. Three distinct phases were observed. Phase A was tissue denaturation. Phase B started with explosive vaporisation ('popcorn') in conjunction with a drop of about 50% in light transmission due to enhanced reflection and scattering. The 'popcorn' is possibly associated with a layered structure of the tissue. Phase C started with carbonisation of the tissue beginning in the centre and expanding in a cyclic fashion while the tissue was vaporised leaving a crater. Forward light transmission did not decrease. Thin layers of carbon (20 mu m) and vacuoles (30 mu m) suggested a large temperature gradient along the tissue ablation front. The ablation velocity was constant (r>0.92) and tissue dependent. Reported models on laser tissue ablation need to be extended to include explosive vaporisation ('popcorn') at the onset and cyclic carbonisation during steady-state crater formation.

Original languageEnglish
Article number009
Pages (from-to)1129-1144
Number of pages16
JournalPhysics in medicine and biology
Volume35
Issue number8
DOIs
Publication statusPublished - 1 Dec 1990
Externally publishedYes

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