Abstract
Original language | Undefined |
---|---|
Pages (from-to) | 103-109 |
Journal | Journal of chromatography A |
Volume | 974 |
Issue number | 1-2 |
DOIs | |
Publication status | Published - 2002 |
Keywords
- IR-38114
- METIS-208821
Cite this
}
Fast liquid chromatography/electrochemistry/mass spectrometry of ferrocenecarboxylic acid esters. / Diehl, J.G.R.; Karst, U.
In: Journal of chromatography A, Vol. 974, No. 1-2, 2002, p. 103-109.Research output: Contribution to journal › Article › Academic › peer-review
TY - JOUR
T1 - Fast liquid chromatography/electrochemistry/mass spectrometry of ferrocenecarboxylic acid esters
AU - Diehl, J.G.R.
AU - Karst, U.
PY - 2002
Y1 - 2002
N2 - Rapid liquid chromatographic separations of ferrocenecarboxylic esters of various alcohols and phenols have been achieved on reversed-phase columns of 20 mm length. After separation, the ferrocene derivatives are oxidized electrochemically under formation of the charged ferrocinium species, which are easily detected by mass spectrometry using an atmospheric pressure chemical ionization source operated in the heated nebulizer mode. While a series of nine phenol derivatives was separated within less than 1.5 min, six alcohol derivatives eluted within 1 min. Limits of detection using a single quadrupole mass analyzer ranged from 60 to 190 nmol/l. Additional work was directed on the use of a graphite in-line filter instead of a silica-based reversed-phase column to achieve the separation.
AB - Rapid liquid chromatographic separations of ferrocenecarboxylic esters of various alcohols and phenols have been achieved on reversed-phase columns of 20 mm length. After separation, the ferrocene derivatives are oxidized electrochemically under formation of the charged ferrocinium species, which are easily detected by mass spectrometry using an atmospheric pressure chemical ionization source operated in the heated nebulizer mode. While a series of nine phenol derivatives was separated within less than 1.5 min, six alcohol derivatives eluted within 1 min. Limits of detection using a single quadrupole mass analyzer ranged from 60 to 190 nmol/l. Additional work was directed on the use of a graphite in-line filter instead of a silica-based reversed-phase column to achieve the separation.
KW - IR-38114
KW - METIS-208821
U2 - 10.1016/S0021-9673(02)01310-9
DO - 10.1016/S0021-9673(02)01310-9
M3 - Article
VL - 974
SP - 103
EP - 109
JO - Journal of chromatography A
JF - Journal of chromatography A
SN - 0021-9673
IS - 1-2
ER -