Feasibility of optical waveguide immunosensors for pesticide detection: physical aspects

E.F. Schipper, R.P.H. Kooyman, R.G. Heideman, J. Greve

Research output: Contribution to journalArticleAcademicpeer-review

30 Citations (Scopus)
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Abstract

The feasibility of detecting small molecules such as pesticides using optical evanescent-wave sensors is discussed with emphasis on the Mach-Zehnder sensor and a newly developed sensor called a ‘critical’ sensor. For direct detection of an estimated average pesticide layer growth of 2×10−4 nm, the sensitivity of the Mach-Zehnder sensor is almost adequate (1×10−3 nm within one hour), whereas that of the ‘critical’ sensor (2×10−2 nm) is not sufficient. However, the simplicity of this latter sensor is very attractive. Results of α-hSA/hSA immunoreaction experiments obtained with this last type of sensor are presented.
Original languageEnglish
Pages (from-to)90-93
Number of pages4
JournalSensors and actuators
Volume24-25
Issue number24-25
DOIs
Publication statusPublished - 1995

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