Feasibility of quantitative determination of local optical absorbances in tissue-mimicking phantoms using acousto-optic sensing

A. Bratchenia, Robert Molenaar, R.P.H. Kooyman

Research output: Contribution to journalArticleAcademicpeer-review

11 Citations (Scopus)


We have investigated the application of ultrasound modulation of coherent light for quantitative determination of local absorbances in tissue-mimicking phantoms. An Intralipid-based phantom model, which mimics a blood vessel in human tissue, was used. The detection technique was based on homodyne parallel speckle detection in transmission mode. Based on a comparison of experimental data and Monte Carlo simulations, a quantitative correlation between local absorbances of the phantom and the measured signal has been shown. The use of microsecond pulses of ultrasound and laser light resulted in a spatial resolution of the system of a few millimeters
Original languageUndefined
Pages (from-to)113901-
JournalApplied physics letters
Issue number11
Publication statusPublished - 2008


  • METIS-248975
  • IR-76399

Cite this