Feasibility study evaluating a magnetic marker in an ex-vivo porcine model

Mirjam C.L. Peek; Ali Zada; Muneer Ahmed; Rose Baker; Masaki Sekino; Moriaki Kusakabe; Michael Douek

doi:10.1016/j.jmmm.2018.01.030

Feasibility study evaluating a magnetic marker in an ex-vivo porcine model

Mirjam C.L. Peek^*, Ali Zada, Muneer Ahmed, Rose Baker, Masaki Sekino, Moriaki Kusakabe, Michael Douek

^*Corresponding author for this work

Technical Medicine

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Abstract

Aims: The magnetic technique using a magnetic tracer and handheld magnetometer was successfully evaluated in breast surgery. Residual tracer at the injection site can cause susceptibility artefacts on breast magnetic resonance imaging (MRI), therefore for lesion localization a solid marker would be preferable. Four magnetic markers were developed for localization to evaluate its clinical applicability. Methods: Comparison was made of the maximum magnetic counts and artefact-volume on MRI. Results: All markers were successfully detected, the spring marker showed the highest mean magnetic counts (627.8 ± 400.2, mean ± SD) with unequal variances (p <.001) and the butterfly marker showed the smallest mean artefact-volume (11.1 ± 2.3 cm³) with a significant difference between markers (p =.049). Conclusion: Localization using a magnetic marker is feasible and further evaluation is required within a clinical trial.

Original language	English
Pages (from-to)	334-339
Number of pages	6
Journal	Journal of magnetism and magnetic materials
Volume	460
DOIs	https://doi.org/10.1016/j.jmmm.2018.01.030
Publication status	Published - 15 Aug 2018

Keywords

Lesion localization
Magnetic markers
Magnetic technique
Magnetometer
Porcine model

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10.1016/j.jmmm.2018.01.030

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title = "Feasibility study evaluating a magnetic marker in an ex-vivo porcine model",

abstract = "Aims: The magnetic technique using a magnetic tracer and handheld magnetometer was successfully evaluated in breast surgery. Residual tracer at the injection site can cause susceptibility artefacts on breast magnetic resonance imaging (MRI), therefore for lesion localization a solid marker would be preferable. Four magnetic markers were developed for localization to evaluate its clinical applicability. Methods: Comparison was made of the maximum magnetic counts and artefact-volume on MRI. Results: All markers were successfully detected, the spring marker showed the highest mean magnetic counts (627.8 ± 400.2, mean ± SD) with unequal variances (p <.001) and the butterfly marker showed the smallest mean artefact-volume (11.1 ± 2.3 cm3) with a significant difference between markers (p =.049). Conclusion: Localization using a magnetic marker is feasible and further evaluation is required within a clinical trial.",

keywords = "Lesion localization, Magnetic markers, Magnetic technique, Magnetometer, Porcine model",

author = "Peek, {Mirjam C.L.} and Ali Zada and Muneer Ahmed and Rose Baker and Masaki Sekino and Moriaki Kusakabe and Michael Douek",

year = "2018",

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doi = "10.1016/j.jmmm.2018.01.030",

language = "English",

volume = "460",

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journal = "Journal of magnetism and magnetic materials",

issn = "0304-8853",

publisher = "Elsevier",

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TY - JOUR

T1 - Feasibility study evaluating a magnetic marker in an ex-vivo porcine model

AU - Peek, Mirjam C.L.

AU - Zada, Ali

AU - Ahmed, Muneer

AU - Baker, Rose

AU - Sekino, Masaki

AU - Kusakabe, Moriaki

AU - Douek, Michael

PY - 2018/8/15

Y1 - 2018/8/15

N2 - Aims: The magnetic technique using a magnetic tracer and handheld magnetometer was successfully evaluated in breast surgery. Residual tracer at the injection site can cause susceptibility artefacts on breast magnetic resonance imaging (MRI), therefore for lesion localization a solid marker would be preferable. Four magnetic markers were developed for localization to evaluate its clinical applicability. Methods: Comparison was made of the maximum magnetic counts and artefact-volume on MRI. Results: All markers were successfully detected, the spring marker showed the highest mean magnetic counts (627.8 ± 400.2, mean ± SD) with unequal variances (p <.001) and the butterfly marker showed the smallest mean artefact-volume (11.1 ± 2.3 cm3) with a significant difference between markers (p =.049). Conclusion: Localization using a magnetic marker is feasible and further evaluation is required within a clinical trial.

AB - Aims: The magnetic technique using a magnetic tracer and handheld magnetometer was successfully evaluated in breast surgery. Residual tracer at the injection site can cause susceptibility artefacts on breast magnetic resonance imaging (MRI), therefore for lesion localization a solid marker would be preferable. Four magnetic markers were developed for localization to evaluate its clinical applicability. Methods: Comparison was made of the maximum magnetic counts and artefact-volume on MRI. Results: All markers were successfully detected, the spring marker showed the highest mean magnetic counts (627.8 ± 400.2, mean ± SD) with unequal variances (p <.001) and the butterfly marker showed the smallest mean artefact-volume (11.1 ± 2.3 cm3) with a significant difference between markers (p =.049). Conclusion: Localization using a magnetic marker is feasible and further evaluation is required within a clinical trial.

KW - Lesion localization

KW - Magnetic markers

KW - Magnetic technique

KW - Magnetometer

KW - Porcine model

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DO - 10.1016/j.jmmm.2018.01.030

M3 - Article

AN - SCOPUS:85045657575

SN - 0304-8853

VL - 460

SP - 334

EP - 339

JO - Journal of magnetism and magnetic materials

JF - Journal of magnetism and magnetic materials

ER -

Feasibility study evaluating a magnetic marker in an ex-vivo porcine model

Abstract

Keywords

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