A fibre-optic sensor capable of detecting an immune reaction between fluorescently labelled antigens and antibodies bound at the waveguide surface is described. In a configuration where skew rays were detected, a signal level was found that made detection of a concentration of 10−9 M antigen possible.
- Fibre-optic sensor
- Immune reactions
Eenink, R. G., de Bruijn, H. E., Kooyman, R. P. H., & Greve, J. (1990). Fibre-fluorescence immunosensor based on evanescent wave detection. Analytica chimica acta, 238, 317-321. https://doi.org/10.1016/S0003-2670(00)80553-X