Fibre-fluorescence immunosensor based on evanescent wave detection

R.G. Eenink, H.E. de Bruijn, R.P.H. Kooyman, Jan Greve

Research output: Contribution to journalArticleAcademicpeer-review

14 Citations (Scopus)
104 Downloads (Pure)

Abstract

A fibre-optic sensor capable of detecting an immune reaction between fluorescently labelled antigens and antibodies bound at the waveguide surface is described. In a configuration where skew rays were detected, a signal level was found that made detection of a concentration of 10−9 M antigen possible.
Original languageEnglish
Pages (from-to)317-321
Number of pages5
JournalAnalytica chimica acta
Volume238
DOIs
Publication statusPublished - 1990

Keywords

  • Fibre-optic sensor
  • METIS-129417
  • Immune reactions
  • IR-72825

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