Five-year outcomes of mechano-chemical ablation of primary great saphenous vein incompetence

Naomi D.E. Thierens, Suzanne Holewijn*, Wynand H.P.M. Vissers, Debbie A.B. Werson, Jean Paul PM de Vries, Michel M.P.J. Reijnen

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Objective: The aim of the study is to report long-term results after mechano-chemical ablation for the treatment of great saphenous vein incompetence. Methods: Mechano-chemical ablation was performed using the ClariVein device with polidocanol as the sclerosant. Clinical-Etiologic-Anatomic-Pathophysiologic (CEAP) classification, Venous-Clinical-Severity-Score (VCSS), anatomical-success, RAND-SF36 and the Aberdeen-Varicose-Vein-Questionnaire (AVVQ) were obtained by clinical examination, questionnaires and duplex ultrasonography through five years’ follow-up (Clinicaltrials.gov, NCT01459263). Results: Ninety-four patients (113 great saphenous veins) were included in the study. Five-year follow-up data were available for 75 limbs (66.4%). Freedom from anatomical failure was 78.7% (N = 45) with 64.6% (N = 42) having an improvement in the VCSS ≥1. A total of five reinterventions were performed through five years with a median time to reintervention of 38 months. The VCSS at five years was 2 (IQR 1; 4) and was still significantly improved compared to baseline (p < 0.001). A deterioration of the VCSS was observed in 21.5%. Conclusion: Through five-year follow-up, there are a significant number of anatomical and clinical failures in this series, mainly driven by partial recanalizations.

Original languageEnglish
Pages (from-to)255-261
Number of pages7
JournalPhlebology
Volume35
Issue number4
Early online date10 Jul 2019
DOIs
Publication statusPublished - 1 May 2020

Keywords

  • Chronic venous insufficiency
  • mechano-chemical ablation
  • patient-reported outcomes
  • quality of life
  • venous severity score

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