Abstract
Laminar flow patterning is an iconic microfluidic technology used to locally deliver chemicals to specific regions on a two-dimensional surface with high spatial fidelity. Here we present a novel extension of this technology by flow patterning inside cured, three-dimensional (3D) hydrogels. We control the pressures at the inlets to shape the size and position of a region of high solute concentration in the main channel filled with a cured collagen 1 hydrogel. This method allows solutes to be delivered with 50 micron accuracy within the gel, as evidenced by control of concentration profiles of 40 kDa fluorescent dye.
| Original language | English |
|---|---|
| Title of host publication | MicroTAS 2018 |
| Subtitle of host publication | The 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences |
| Editors | Gwo-Bin Lee, Fan-Gang Tseng |
| Publisher | The Chemical and Biological Microsystems Society |
| Pages | 2239-2241 |
| Number of pages | 3 |
| ISBN (Electronic) | 978-1-510-89757-1 |
| ISBN (Print) | 978-0-578-40530-8 |
| Publication status | Published - 11 Nov 2018 |
| Event | 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2018 - Kaohsiung Exhibition Center, Kaohsiung, Taiwan Duration: 10 Nov 2018 → 15 Nov 2018 Conference number: 22 https://cbmsociety.org/conferences/microtas2018/ |
Conference
| Conference | 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2018 |
|---|---|
| Abbreviated title | MicroTAS 2018 |
| Country/Territory | Taiwan |
| City | Kaohsiung |
| Period | 10/11/18 → 15/11/18 |
| Internet address |
Keywords
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