Fluorescence monitoring of microchip capillary electrophoresis separation with monolithically integrated optical waveguides

C. Dongre, R. Dekker, Hugo Hoekstra, R. Martinez-Vazquez, R. Osellame, R. Ramponi, G. Cerullo, R. van Weeghel, G.A.J. Besselink, H.H. van den Vlekkert, Markus Pollnau

    Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

    Abstract

    Femtosecond-laser-written waveguides were integrated with fluidic microchannels in a commercial lab-on-a-chip. High-spatial-resolution monitoring of fluorescently labeled DNA molecules during capillary electrophoresis separation is demonstrated, as an intermediate step toward point-of-care diagnostic bioassays for DNA analysis.
    Original languageEnglish
    Title of host publicationConference on Lasers and Electro-Optics, 2009 and 2009 Conference on Quantum electronics and Laser Science Conference. CLEO/QELS 2009
    Place of PublicationWashington, D.C.
    PublisherOptical Society of America
    PagesCTuM5
    Number of pages2
    ISBN (Print)978-1-55752-869-8
    DOIs
    Publication statusPublished - Jun 2009
    EventEuropean Conference on Lasers and Electro-Optics and the XIth European Quantum Electronics Conference (CLEO®/Europe-EQEC) 2009: Explore Innovation. Build Applications. - Baltimore Convention Center, Munich, Germany
    Duration: 14 Jun 200919 Jun 2009

    Conference

    ConferenceEuropean Conference on Lasers and Electro-Optics and the XIth European Quantum Electronics Conference (CLEO®/Europe-EQEC) 2009
    Abbreviated titleCLEO/Europe-EQEC 2009
    CountryGermany
    CityMunich
    Period14/06/0919/06/09

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    Keywords

    • Integrated Optics devices
    • Glass waveguides
    • Fluorescence
    • Biological sensing and sensors
    • IOMS-SNS: SENSORS
    • Optical sensing and sensors
    • Laser materials processing
    • EC Grant Agreement nr.: FP6/034562

    Cite this

    Dongre, C., Dekker, R., Hoekstra, H., Martinez-Vazquez, R., Osellame, R., Ramponi, R., ... Pollnau, M. (2009). Fluorescence monitoring of microchip capillary electrophoresis separation with monolithically integrated optical waveguides. In Conference on Lasers and Electro-Optics, 2009 and 2009 Conference on Quantum electronics and Laser Science Conference. CLEO/QELS 2009 (pp. CTuM5). Washington, D.C.: Optical Society of America. https://doi.org/10.1364/CLEO.2009.CTuM5