Fluorescence monitoring of microchip capillary electrophoresis separation with monolithically integrated optical waveguides

C. Dongre, R. Dekker, Hugo Hoekstra, R. Martinez-Vazquez, R. Osellame, R. Ramponi, G. Cerullo, R. van Weeghel, G.A.J. Besselink, H.H. van den Vlekkert, Markus Pollnau

    Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

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    Abstract

    Femtosecond-laser-written waveguides were integrated with fluidic microchannels in a commercial lab-on-a-chip. High-spatial-resolution monitoring of fluorescently labeled DNA molecules during capillary electrophoresis separation is demonstrated, as an intermediate step toward point-of-care diagnostic bioassays for DNA analysis.
    Original languageEnglish
    Title of host publicationConference on Lasers and Electro-Optics, 2009 and 2009 Conference on Quantum electronics and Laser Science Conference. CLEO/QELS 2009
    Place of PublicationWashington, D.C.
    PublisherOptical Society of America
    PagesCTuM5
    Number of pages2
    ISBN (Print)978-1-55752-869-8
    DOIs
    Publication statusPublished - Jun 2009
    EventEuropean Conference on Lasers and Electro-Optics and the XIIth European Quantum Electronics Conference (CLEO®/Europe-EQEC) 2009: Explore Innovation. Build Applications. - Baltimore Convention Center, Munich, Germany
    Duration: 22 May 201126 May 2011

    Conference

    ConferenceEuropean Conference on Lasers and Electro-Optics and the XIIth European Quantum Electronics Conference (CLEO®/Europe-EQEC) 2009
    Abbreviated titleCLEO-Europe/EQEC 2011
    Country/TerritoryGermany
    CityMunich
    Period22/05/1126/05/11

    Keywords

    • Integrated Optics devices
    • Glass waveguides
    • Fluorescence
    • Biological sensing and sensors
    • IOMS-SNS: SENSORS
    • Optical sensing and sensors
    • Laser materials processing
    • EC Grant Agreement nr.: FP6/034562

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